Baseline characteristics and clinical outcome during follow-up
| Transcatheter aortic valve implantation n=89 | |
|---|---|
| Baseline—cardiological assessment | |
| Age, mean (SD), year | 80.4 (6.3) |
| Weight, mean (SD), kg | 73.6 (15.0) |
| Body mass index, mean (SD), kg/m2 | 26.9 (4.9) |
| Gender, male, n (%) | 38 (43) |
| Renal impairment <50 mL/min/1.73 m2, n (%) | 47 (53) |
| Extracardiac arteriopathy, n (%) | 24 (27) |
| Subjective poor mobility, n (%) | 8 (9) |
| Previous cardiac surgery, n (%) | 1 (1) |
| Chronic lung disease, n (%) | 20 (22) |
| Diabetes on insulin, n (%) | 24 (27) |
| New York Heart Association (classification) III or IV, n (%) | 77 (87) |
| Ejection fraction ≤30%, n (%) | 5 (6) n=78 |
| Pulmonary hypertension >30 mm Hg, n (%) | 55 (72) n=76 |
| EuroSCORE I, mean (SD) | 15.9 (9.8) |
| EuroSCORE II, mean (SD) | 5.4 (5.0) |
| Aortic valve area, mean (SD), cm2 | 0.72 (0.25) |
| Aortic valve peak gradient, mean (SD), mm Hg | 75.7 (22.6) |
| Baseline—frailty assessment | |
| Mini Mental State Examination (range 0–30), mean (SD) | 27.0 (2.5) |
| Basic Activities of Daily Living (range 0–20), mean (SD) | 18.5 (1.8) |
| Instrumental Activities of Daily Living (range 0–8), mean (SD) | 6.4 (2.0) |
| Gait speed, mean (SD), m/s | 0.84 (0.3) |
| Timed Up and Go, mean (SD), seconds | 12.8 (6.2) |
| Mini Nutritional Assessment (range 0–14), mean (SD) | 11.7 (2.5) |
| Frailty Index (range 0–5), mean (SD) | 2.38 (1.47) |
| Clinical judgement frail, n (%) | 47 (53) |
| Clinical judgement high risk for delirium, n (%) | 65 (73) |
| Clinical outcome | |
| TIA/CVA, n (%) | 1 (1) |
| Renal failure, n (%) | 0 (0) |
| Gastric bleeding, n (%) | 1 (1) |
| Vascular complications, n (%) | 3 (3) |
| Postprocedural incidence of delirium, in-hospital, n (%) | 25 (28) |
| Mortality (all-cause), median follow-up 195 days (IQR 69–321 days), n (%) | 11 (12) |
CVA, Cerebrovascular Accident; EuroSCORE, European System for Cardiac Operative Risk Evaluation; TIA, Transient Ischemic Attack.