Table 6

Multivariable associations of T-wave and other ECG changes with (1) sudden CHD death and (2) non-sudden CHD death*

Sudden death (n=184)No sudden death (n=1983)Adjusted* HR95% CIp Value
(1) Sudden death
 High-risk ECG abnormality
  Without T-wave changes131141.400.78 to 2.52
  T-wave changes‡21532.601.58 to 4.29
 T-wave changes
  Present21532.521.52 to 4.18
 Q/QS pattern
  Present4241.110.39 to 3.16
  Present10801.290.66 to 2.49
Non-sudden CHD death (n=78)No non-sudden CHD death (n=2089)Adjusted* HR95% CIp Value
(2) Non-sudden CHD death
 High-risk ECG abnormality
  Without T-wave changes31240.620.19 to 2.04
  T-wave changes‡2720.470.11 to 1.99
 T-wave changes
  Present2720.460.11 to 1.97
 Q/QS pattern
  Present2262.310.51 to 10.53
  Present1890.240.03 to 1.81
  • *Adjusted for age, peak flow rate, systolic blood pressure, body mass index, smoking status, previous angina, cholesterol, fibrinogen, factor VII, triglycerides, platelets, white cell count, red blood cell count, haemoglobin, packed cell volume, alcohol use, social class, factor V and factor VIII.

  • †Trend test.

  • ‡Broken down by the presence of ST depression: T-wave alone: sudden deaths=13, non-sudden CHD deaths=1, non-CHD death/alive=40.

  • T-wave and ST depression: sudden deaths=8, non-sudden CHD deaths=1, non-CHD death/alive=11. For (1) sudden death: adjusted HR=2.31 (95% CI 1.27 to 4.19) (T-wave alone); 3.07 (95% CI 1.39 to 6.78 (T-wave and ST depression). For (2) non-sudden CHD death: adjusted HR=0.33 (95% CI 0.05 to 2.46) (T-wave alone); 0.89 (95% CI 0.11 to 7.07 (T-wave and ST depression).

  • CHD, coronary heart disease.