Table 1

Typical treatment strategies of events included in the CM

Cardiovascular events
 Cerebrovascular accidentConservative management (antiplatelets and/or anticoagulants and watchful waiting)
Thrombolysis (in-hospital)
Mechanical thrombectomy
 Myocardial infarctionConservative management
Percutaneous coronary intervention
Coronary artery bypass grafting
 Vascular complicationConservative management (in-hospital monitoring with duplex sonography)
Endovascular stent or balloon therapy
Surgical repair
 BleedingOptimization of anticoagulation control
Blood transfusion
Surgical repair of bleeding location
 Atrial fibrillation (without PI)Medication (anticoagulants)
Electric cardioversion
 Conduction disturbances and arrhythmiasPacemaker implantation (PI)†
Non-cardiovascular events
 Acute kidney injuryConservative management (diuretics to correct volume overload)
Continuous veno-venous hemofiltration
Chronic dialysis
Kidney transplant
Prosthetic valve-related events
 Prosthetic valve dysfunctionConservative management (heart failure medication and watchful waiting)
 Prosthetic valve thrombosisThrombolysis (in-hospital)
Re-intervention: valve replacement
 Prosthetic valve endocarditisAntibiotic treatment (in-hospital)
Re-intervention: valve replacement
  • *Re-intervention can be surgical repair or replacement/valve-in-valve implantation of another valve substitute.

  • †Patients with conduction disturbances and arrhythmias other than atrial fibrillation without the need for pacemaker implantation are excluded.

  • CM: conceptual model.