Comparison of HRQoL outcomes at follow-up for home-based and centre-based cardiac rehabilitation
| Trial Author (year) | Follow-up | HRQoL measure | Outcome values at follow-up or mean difference (95% CI) Mean (SD) Home vs centre, between group p value | Between-group difference |
|---|---|---|---|---|
| Bell (1998) | 10.5 months | Nottingham Health Profile | ||
| Energy | 18.6 (28.4) vs 17.3 (30.7) p=0.78* | Home=centre | ||
| Pain | 6.6 (15.3) vs 7.4 (15.5) p=0.74* | Home=centre | ||
| Emotional reactions | 6.6 (15.3) vs 7.4 (15.5) p=0.74* | Home=centre | ||
| Sleep | 6.6 (15.3) vs 16.9 (22.8) p=0.0007* | Home<centre | ||
| Social isolation | 3.7 (13.6) vs 6.7 (15.0) p=0.18* | Home=centre | ||
| Physical mobility | 6.9 (13.5) vs 9.1 (15.9) p=0.33* | Home=centre | ||
| Arthur et al (2002)/Smith et al (2004)60 | 6 months | SF-36 PCS | 51.2 (6.4) vs 48.6 (7.1) p=0.003* | Home>centre |
| MCS | 53.5 (6.4) vs 52.0 (8.1) p=0.13* | Home=centre | ||
| 18 months | SF-36 PCS | 48.3 (11.7) vs 47.6 (11.7) p=0.67* | Home=Centre | |
| MCS | 53.0 (10.9) vs 50.2 (10.9) p=0.07* | Home=centre | ||
| Cowie et al (2012) | 3 months | SF-36 PCS | 34.01 (11.04) vs 31.33 (7.97) p=0.82 | Home=centre |
| MCS | 44.44 (12.23) vs 48.25 (11.21) p=0.04 | Home<centre | ||
| MLWHF total | 37 (NR) vs 32 (NR) p=0.18 | Home=centre | ||
| Physical | 21 (NR) vs 19 (NR) p=0.31 | Home=centre | ||
| Emotional | 7 (NR) vs 7 (NR) p=0.13 | Home=centre | ||
| Marchionni et al (2003) | 2 months | Sickness Impact Profile | 2.83 (14.5) vs 4.71 (11.1) p=0.09* | Home=centre |
| 8 months | 2.83 (14.5) vs 3.40 (11.1) p=0.61* | Home=centre | ||
| 14 months | 2.00 (8.3) vs 3.70 (11.8) p=0.06* | Home=centre | ||
| Dalal et al (2007)/Taylor et al (2007)61 | 9 months | MacNew Global Score | 5.61 (1.14) vs 5.54 (1.10) p=0.71 | Home=centre |
| EQ-5D | 0.74 (0.04) vs 0.78 (0.04) p=0.57 | Home=centre | ||
| Jolly et al (2007) | 6 months | EQ-5D | 0.74 (0.26) vs 0.76 (0.23) p=0.37 | Home=centre |
| SF-12 PCS | 42.28 (10.9) vs 42.56 (10.8) p=0.8 | Home=centre | ||
| MCS | 49.19 (10.1) vs 50.33 (9.6) p=0.3 | Home=centre | ||
| 12 months | EQ-5D | 0.74 (0.27) vs 0.76 (0.23) p=0.52* | Home=centre | |
| 24 months | EQ-5D | 0.73 (0.29) vs 0.75 (0.26) p=0.39* | Home=centre | |
| Karapolat et al (2009) | 8 weeks | SF-36 | ||
| Physical function | 59.39 (25.35) vs 69.57 (20.94), p=0.08* | Home=centre | ||
| Physical role | 39.81 (41.75) vs 48.21 (45.10) p=0.43* | Home=centre | ||
| Bodily pain | 62.42 (30.45) vs 74.23 (19.66) p=0.07* | Home=centre | ||
| General health | 47.25 (23.42) vs 53.98 (25.00) p=0.33* | Home=centre | ||
| Vitality | 66.67 (19.82) vs 69.81 (17.41) p=0.49* | Home=centre | ||
| Social function | 65.33 (25.60) vs 69.33 (25.14) p=0.52* | Home=centre | ||
| Emotional role | 44.74 (39.77) vs 37.16 (39.24) p=0.44* | Home=centre | ||
| Mental health | 64.67 (19.04) vs 70.52 (20.37) p=0.22* | Home=centre | ||
| Moholdt et al (2012) | 6 months | MacNew | ||
| Emotional domain | 1.2 (0.2) vs 1.4 (0.2) p>0.05 | Home=centre | ||
| Physical domain | 1.4 (0.7) vs 1.6 (1.1) p>0.05 | Home=centre | ||
| Social domain | 4.3 (0.7) vs 4.3 (1.0) p>0.05 | Home=centre | ||
| Oerkild et al (2011) | 3 months | SF-36 PCS | 1.4 (−1.5 to 4.3) vs, 0.5 (−2.4 to 3.4), p>0.05 | Home=centre |
| SF-36 MCS | 0.8 (−2.6 to 4.3) vs −0.2 (−3.6 to 3.4), p>0.05 | Home=centre | ||
| 6 months | SF-36 PCS | 1.0 (−1.6 to 3.6) vs 1.2 (−1.4 to 3.8), p>0.05 | Home=centre | |
| SF-36 MCS | 2.3 (−1.1 to 5.7) vs 2.6 (−0.9 to −6.0), p>0.05 | Home=centre | ||
| Piotrowicz et al (2010) | 8 weeks | SF-36 total | 70.5 (25.4) vs 69.2 (26.4) (p>0.05) | Home=centre |
*p Value calculated by authors of this report based on an independent two-group t-test.
Home=centre: no statistically significant difference (p≥0.05) in HRQoL between home-based and centre-based groups at follow-up.
Home>centre: statistically significant (p<0.05) higher HRQoL in home-based versus centre-based groups at follow-up.
Home<centre: statistically significant (p<0.05) lower HRQoL in home-based versus centre-based groups at follow-up.
HRQoL, health-related quality of life; MCS, mental component score; MLWHF, Minnesota Living With Heart Failure; NR, not reported; PCS, physical component score; SF-12, 12-item Short Form Health Survey; SF-36, Short Form (36) Health Survey.