Baseline characteristics, stratified by eligibility and recruitment status
| All patients screened (A) n=629 | Eligible patients (B) n=457 | Recruited patients (C) n=300 | Non-recruited patients (D) n=157 | p Values for difference between groups | |||
|---|---|---|---|---|---|---|---|
| A vs B | B vs C | C vs D | |||||
| Female (%) | 275 (43.7) | 210 (46.0) | 117 (39.0) | 93 (59.2) | 0.310 | 0.033* | <0.001*** |
| Age (years) | 81.2±4.8 | 81.1±4.7 | 80.5±4.7 | 82.2±4.7 | 0.231 | 0.100 | <0.001*** |
| Presentation | |||||||
| NSTEMI (%) | 458 (72.8) | 348 (76.1) | 246 (82.0) | 105 (66.9) | |||
| UA (%) | 86 (13.7) | 67 (14.7) | 51 (17.0) | 19 (12.1) | 0.032* | <0.001*** | <0.001*** |
| Other (%) | 85 (13.5) | 38 (8.3) | 3 (1.0) | 33 (21.0) | |||
| Hypertension (%) | 475 (75.5) | 342 (74.8) | 225 (75.0) | 117 (74.5) | 0.797 | 0.959 | 0.911 |
| Diabetes (%) | 162 (25.8) | 112 (24.5) | 70 (23.3) | 42 (26.8) | 0.640 | 0.712 | 0.420 |
| Smoking status | |||||||
| Current smoker (%) | 37 (5.9) | 28 (6.1) | 17 (5.7) | 11 (7.0) | |||
| Ex-smoker (%) | 377 (59.9) | 251 (54.9) | 162 (54.0) | 89 (56.7) | 0.242 | 0.914 | 0.648 |
| Never smoked (%) | 215 (34.2) | 178 (38.9) | 121 (40.3) | 57 (36.3) | |||
| Hypercholesterolaemia (%) | 358 (56.9) | 264 (57.8) | 180 (60.0) | 84 (53.5) | 0.779 | 0.541 | 0.181 |
| Family history of IHD (%) | 160 (25.4) | 125 (27.4) | 97 (32.3) | 28 (17.8) | 0.479 | 0.141 | <0.001*** |
| Renal impairment (%) | 159 (25.3) | 107 (23.4) | 68 (22.7) | 39 (24.8) | 0.481 | 0.812 | 0.602 |
| Previous MI (%) | 221 (35.1) | 147 (32.2) | 95 (31.7) | 52 (33.1) | 0.308 | 0.885 | 0.651 |
| Previous PCI (%) | 138 (21.9) | 95 (20.8) | 61 (20.3) | 34 (21.7) | 0.648 | 0.880 | 0.741 |
| Peripheral vascular disease (%) | 63 (10.0) | 42 (9.2) | 28 (9.3) | 14 (8.9) | 0.649 | 0.947 | 0.883 |
| Cerebrovascular disease (%) | 80 (12.7) | 57 (12.5) | 44 (14.7) | 13 (8.3) | 0.904 | 0.489 | 0.065 |
| Radial access (%) | 549 (87.3) | 411 (89.9) | 268 (89.3) | 143 (91.1) | 0.178 | 0.790 | 0.555 |
| Treatment | |||||||
| PCI (%) | 456 (72.5) | 349 (76.4) | 251 (83.7) | 98 (62.4) | |||
| CABG (%) | 17 (2.7) | 11 (2.4) | 8 (2.7) | 3 (1.9) | 0.354 | 0.310 | <0.001*** |
| Medical management (%) | 156 (24.8) | 97 (21.2) | 41 (13.7) | 56 (35.7) | |||
| Number of stents in those receiving PCI | 1.7±1.3 | 1.7±1.2 | 1.8±1.1 | 1.6±1.4 | 0.932 | 0.534 | 0.142 |
Continuous variables are presented in the form of mean±SD, and discrete variables are presented in the form of n (%).
*Significant at p<0.05 level, **significant at p<0.01 level, ***significant at p<0.001 level.
CABG, coronary artery bypass surgery; IHD, ischaemic heart disease; MI, myocardial infarction; NSTEMI, non-ST-elevation myocardial infarction; PCI, percutaneous coronary intervention; UA, unstable angina.