Summary of multilevel linear mixed-effects models for cardiac output, heart rate and stroke volume
| Cardiac output | Heart rate | Stroke volume | ||||
|---|---|---|---|---|---|---|
| Variable | Estimate (SE) | Estimate (SE) | ||||
| Fixed part | Estimate (SE) | p Value | Fixed part | p Value | Fixed part | p Value |
| Intercept | −7.57 (3.03) | 0.012 | 121.52 (22.89) | <0.001 | −132.3844 (40.88) | 0.001 |
| Time | −0.04 (0.05) | 0.398 | −1.55 (0.44) | <0.001 | 0.70 (0.59) | 0.239 |
| Age | −0.02 (0.02) | 0.202 | −0.23 (0.15) | 0.133 | 0.036 (0.28) | 0.898 |
| Height | 0.04 (0.03) | 0.174 | −0.09 (0.25) | 0.712 | 0.96 (0.45) | 0.033 |
| Weight | −0.01 (0.03) | 0.787 | 0.204 (0.29) | 0.495 | 0.23 (0.533) | 0.664 |
| BSA | 4.45 (3.84) | 0.246 | −13.07 (29.00) | 0.653 | 14.36 (51.68) | 0.781 |
| Parous—previous PE | 0.79 (0.31) | 0.012 | 2.97 (2.38) | 0.213 | 4.45 (4.26) | 0.296 |
| Parous—no previous PE | 0.70 (0.34) | 0.038 | 3.97 (2.57) | 0.1123 | 2.01 (4.59) | 0.661 |
| Ethnicity | −0.008 (0.06) | 0.884 | 0.32 (0.45) | 0.481 | −0.26 (0.82) | 0.751 |
| Random part Variances (expressed in SD) due to random effects | Random part Variances (expressed in SD) due to random effects | Random part Variances (expressed in SD) due to random effects | ||||
| Individual SD, estimate (SE) | 1.120924 (0.0871327) | 8.245412 (0.6776951) | 15.42569 (1.153087) | |||
| Residual SD, estimate (SE) | 0.7596877 (0.0358327) | 6.585155 (0.3094017) | 8.85682 (0.418325) | |||
| Model specifications | Model specifications | Model specifications | ||||
| Log likelihood | −522.56485 (p<0.001) | −1239.7218 (p=0.01) | −1364.1167 (p<0.001) | |||
| AIC | 1067.13 | 2501.444 | 2750.233 | |||
| BIC | 1109.409 | 2543.786 | 2792.512 | |||
| LR test for random part (null hypothesis: variance due to random effects=0) | p<0.001 | p<0.001 | p<0.001 | |||
The variables are presented as estimates and SEs.
AIC, Akaike information criterion; BIC, Bayesian information criterion; BSA, body surface area; LR, likelihood ratio; PE, pre-eclampsia.