Association of T2DM, history and actual hypertension with abnormal myocardial function
| GLS | DS | DSR | e′ | E/e′ | E/A | LVMi | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ß (95% CI) | p Value | ß (95% CI) | p Value | ß (95% CI) | p Value | ß (95% CI) | p Value | ß (95% CI) | p Value | ß (95% CI) | p Value | ß (95% CI) | p Value | |
| Univariate analysis | ||||||||||||||
| T2DM | 1.383 (0.922 to 1.845) | <0.001 | −0.031 (−0.056 to −0.01) | 0.017 | −0.068 (−0.11 to −0.022) | 0.004 | −0.002 (−0.005 to 0.001) | 0.191 | 0.603 (0.073 to 1.134) | 0.026 | −0.015 (−0.051 to 0.020) | 0.396 | 0.097 (−3.99 to 4.19) | 0.963 |
| History HTN | −0.156 (−0.755 to 0.443) | 0.608 | −0.007 (−0.040 to 0.025) | 0.649 | −0.012 (−0.07 to 0.046) | 0.679 | −0.002 (−0.006 to 0.001) | 0.214 | 0.689 (0.021 to 1.357) | 0.043 | 0.011 (−0.034 to 0.057) | 0.622 | 5.82 (0.695 to 10.94) | 0.026 |
| Active HTN | 0.463 (−0.031 to 0.957) | 0.066 | −0.033 (−0.06 to −0.007) | 0.014 | −0.063 (−0.11 to −0.016) | 0.009 | −0.005 (−0.007 to −0.002) | 0.002 | 0.711 (0.160 to 1.262) | 0.012 | −0.037 (−0.074 to 0.001) | 0.053 | 8.72 (4.53 to 12.92) | 0.000 |
| Model with history of HTN* | ||||||||||||||
| T2DM | 0.972 (0.522 to 1.423) | <0.001 | −0.021 (−0.043 to 0.000) | 0.054 | −0.062 (−0.11 to −0.015) | 0.01 | −0.003 (−0.006 to −0.001) | 0.02 | 0.764 (0.229 to 1.298) | 0.005 | −0.000 (−0.025 to 0.035) | 0.996 | −1.553 (−5/43 to 2.321) | 0.431 |
| History HTN | −0.025 (−0.578 to 0.529) | 0.931 | −0.015 (−0.042 to 0.012) | 0.275 | −0.016 (−0.073 to 0.042) | 0.59 | −0.002 (−0.006 to 0.001) | 0.164 | 0.742 (0.086 to 1.399) | 0.027 | 0.011 (−0.032 to 0.055) | 0.615 | 4.26 (−0.493 to 9.02) | 0.098 |
| Model with active HTN* | ||||||||||||||
| T2DM | 1.00 (0.56 to 1.45) | <0.001 | −0.022 (−0.04 to −0.001) | 0.044 | −0.064 (−0.11 to −0.02) | 0.01 | −0.003 (−0.006 to −0.001) | 0.017 | 0.726 (0.19 to 1.26) | 0.007 | −0.003 (−0.04 to 0.03) | 0.848 | −1.564 (−5.375 to 2.247) | 0.421 |
| Active HTN | 0.408 (−0.05 to 0.86) | 0.079 | −0.035 (−0.06 to −0.013) | 0.002 | −0.059 (−0.11 to −0.013) | 0.013 | −0.005 (−0.007 to −0.002) | 0.001 | 0.691 (0.151 to 1.23) | 0.012 | −0.033 (−0.069 to 0.032) | 0.848 | 7.029 (3.144 to 10.91) | 0.000 |
*Adjusted for age, gender, BMI and HR.
DS, diastolic strain; DSR, diastolic strain rate; GLS, global longitudinal strain; HTN, hypertension; LVMi, left ventricular mass index; T2DM, type 2 diabetes mellitus.