Cathepsin D, cathepsin L and cystatin B levels in incident coronary event (CE) cases compared to controls in individuals without diabetes, non-smokers or smokers
| Controls | Incident CE† | |
|---|---|---|
| Individuals without diabetes (n=680) | ||
| Number of individuals | 375 | 305 |
| Cathepsin D | 160 (126–197) | 174 (139–224)*** |
| Cathepsin L | 52 (42–66) | 54 (43–72)* |
| Cystatin B | 42 (33–51) | 46 (36–57)*** |
| Non-smokers or ex-smokers (n=527) | ||
| Number of individuals | 296 | 231 |
| Cathepsin D | 161 (128–209) | 172 (136–223)* |
| Cathepsin L | 52 (43–67) | 55 (44–72) |
| Cystatin B | 41 (33–51) | 43 (36–56)* |
| Smokers (n=235) | ||
| Number of individuals | 103 | 132 |
| Cathepsin D | 170 (130–218) | 199 (149–251)** |
| Cathepsin L | 51 (41–67) | 59 (45–76)* |
| Cystatin B | 43 (36–54) | 48 (37–58)* |
Values are expressed as median (IQR) in arbitrary units.
*p≤0.05.
**p<0.01.
***p<0.001.
†Mann–Whitney test.