Logistic regression between clinically ascertained and self-reported HT at age 60–64 years and lifetime affective caseness variables (n=1683)
| Clinically ascertained HT vs normotension (982 vs 701) | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cumulative lifetime affective caseness (OR (95% CI))* | Age-specific lifetime affective caseness (OR (95% CI))* | |||||||
| No symptoms (n=1080) | Case-level symptoms at 1–2 time points (n=474) | Case-level symptoms at 3–4 time points (n=129) | p Value† | No symptoms (n=1080) | Case-level symptoms only in the past (n=305) | Case-level symptoms in recent times (n=298) | p Value† | |
| Model 1 | 1.00 | 0.99 (0.79 to 1.23) | 1.10 (0.76 to 1.59) | 0.87 | 1.00 | 0.95 (0.74 to 1.23) | 1.08 (0.83 to 1.40) | 0.75 |
| Model 2 | 1.00 | 0.98 (0.77 to 1.24) | 0.98 (0.64 to 1.47) | 0.83 | 1.00 | 0.93 (0.70 to 1.22) | 1.04 (0.78 to 1.38) | 0.79 |
| Model 3 | 1.00 | 1.01 (0.79 to 1.28) | 1.01 (0.66 to 1.54) | 0.84 | 1.00 | 0.95 (0.72 to 1.26) | 1.07 (0.80 to 1.43) | 0.80 |
| Self-reported HT vs normotension (702 vs 981) | ||||||||
| Model 1 | 1.00 | 1.44 (1.16 to 1.80) | 1.48 (1.03 to 2.14) | 0.001 | 1.00 | 1.32 (1.02 to 1.71) | 1.60 (1.24 to 2.07) | 0.0006 |
| Model 2 | 1.00 | 1.41 (1.11 to 1.78) | 1.22 (0.81 to 1.83) | 0.004 | 1.00 | 1.27 (0.96 to 1.67) | 1.48 (1.12 to 1.97) | 0.01 |
| Model 3 | 1.00 | 1.40 (1.10 to 1.78) | 1.19 (0.79 to 1.80) | 0.02 | 1.00 | 1.26 (0.95 to 1.67) | 1.47 (1.10 to 1.96) | 0.02 |
Model 1: unadjusted logistic regression.
Model 2: logistic regression adjusted for gender, BMI at age 60–64 years, educational attainment by age 26 years, socioeconomic position at age 53 years, history of CVD and diabetes mellitus status at age 60–64 years.
Model 3: model 2 additionally adjusted for covariates at age 60–64 years: heart rate, current smoking, alcohol consumption, physical activity and antidepressant treatment.
*Affective caseness assessed at each time point as follow: PSE-ID≥5 at age 36 years, total PSF score ≥23 at age 43 years, and total GHQ-28 score ≥5 at ages 53 and 60–64 years.
†p Value for trend.
BMI, body mass index; CVD, cardiovascular disease; GHQ-28, General Health Questionnaire–28-items; HT, hypertension; PSE-ID, Present State Examination-Index of Definition; PSF, Psychiatric Symptom Frequency.