Table 1

Characteristics of all patients, stratified by the presence or absence of LGE

All patients (n=76)No LGE (n=37)LGE (n=39)p Value
Age, years54±14.954±14.154.3±15.80.93
Males, %60 (78)31 (84)29 (74)0.31
History of hypertension, %25 (32)15 (41)10 (26)0.16
History of diabetes mellitus, %16 (21)9 (24)7 (18)0.49
History of dyslipidaemia, %20 (26)12 (32)8 (21)0.28
History of smoking, %31 (40)15 (40)16 (41)0.98
History of VF or sustained VT, %15 (20)4 (11)11 (28)0.08
Length of hospital stay25.5±22.420±8.530.6±29.40.03
Clinical variables
Systolic BP, mm Hg123.3±25.4131.7±27.1115.4±21.20.005
Diastolic BP, mm Hg83.3±23.387.0±25.374.1±19.60.017
Heart rate, bpm92.6±25.297.8±26.587.9±23.40.09
Sinus rhythm, %63 (83)30 (81)33 (85)0.68
Complete LBBB, %18 (24)10 (27)8 (21)0.41
NYHA functional class, %
I1100.50
II21129
III361719
IV18711
Medication at baseline, %
β-blocker73 (96)36 (97)37 (95)0.58
ACEi or ARB65 (86)30 (81)35 (90)0.28
Aldosterone antagonist52 (69)27 (73)25 (66)0.5
Loop diuretic51 (67)24 (65)27 (69)0.68
Digoxin9 (12)6 (16)3 (8)0.25
Statin22 (29)10 (27)12 (32)0.66
Aspirin8 (11)5 (13)3 (8)0.40
Warfarin33 (43)17 (46)16 (41)0.66
Amiodarone14 (18)6 (16)8 (20)0.62
Device implantation, %
ICD/CRT-D26 (34)9 (24)17 (43)0.09
Laboratory examination
Haemoglobin, g/dL14.1±2.614.4±2.513.7±2.00.23
Creatinine, mg/dL1.0±0.31.0±0.291.0±0.310.92
Sodium, mmol/L139.6±3.2140.1±3.1139.2±3.20.20
BNP at hospitalisation, pg/mL773.2±661.8740.2±780.2734.3±536.50.97
BNP at stable state, pg/mL290±252.7239.1±233.4338.2±263.80.08
Hs-CRP at hospitalisation, mg/dL0.81±1.530.88±1.50.74±1.50.68
Hs-CRP at stable state, mg/dL0.59±0.880.61±0.90.56±0.80.80
Cardiovascular MR measurements (SD)
LVEDV, mL/m2155.8±71.5149.5±67.5161.8±75.50.45
LVESV, mL/m2124.5±68.4122.0±64.0126.8±73.20.75
LVSV, mL53.9±20.848.6±16.958.9±23.00.028
LVEF, %21.9±9.719.7±6.124±12.00.053
LV mass index, g/m2102.7±34.3103.0±31.7102.7±37.90.97
  • ACEi, ACE inhibitor; ARB, angiotensin receptor blocker; BNP, B-type natriuretic peptide; BP, blood pressure; CRT-D, cardiac resynchronisation therapy combined with a defibrillator; EDV, end-diastolic volume; EF, ejection fraction; ESV, end-systolic volume; Hs-CRP, high-sensitivity C reactive protein; ICD, implantable cardioverter defibrillator; LBBB, left bundle branch block; LV, left ventricular; LVEDV, left ventricular end-diastolic volume; LVESV, left ventricular end-systolic volume; LVEF, left ventricular ejection fraction; NYHA, New York Heart Association; SV, stroke volume; Values are mean±SD or n (%). VF, ventricular fibrillation; VT, ventricular tachycardia.