Table 1

Population characteristics at inclusion (N=102)

Clinical characteristics
 Age, years51±14
 Male gender, n (%)74 (73)
 Body mass index, kg/m228±5
 Systolic blood pressure, mm Hg116±20
 Diastolic blood pressure, mm Hg71±12
 Heart rate, bpm75±16
 Atrial fibrillation, n (%)18 (18)
 NYHA class (I/II/III/IV)15/61/20/6
Medical history
 Smokers, n (%)24 (24)
 History of hypertension, n (%)18 (18)
 Diabetes mellitus prior to the development of heart failure, n (%)4 (4)
 Duration of symptoms, months7 (3–16)
 NYHA class at peak symptom severity (I/II/III/IV)4/15/25/58
 QRS-duration, ms110 (99–134)
 Left bundle branch block, n (%)21 (21)
Laboratory values
 Haemoglobin, g/dL14.4±1.5
 Creatinine, pmol/L86±21
 N-terminal pro-B-type natriuretic peptide, pg/mL1332 (584–2903)
 Left ventricular ejection fraction, %26±10
 Left ventricular end diastolic diameter, cm7.1±0.8
 Left ventricular end diastolic internal volume, mL267 (216–328)
 Cardiac output, L/min4.9±1.4
Cardiac MRI (88 patients)
 Left ventricular ejection fraction, %28±11
 Left ventricular end diastolic internal volume, mL273 (214–356)
 Left ventricular myocardial volume, mL212±62
 Gadolinium late enhancement, n (%)29 (35)
Exercise testing (96 patients)
 Maximum work load, W133±56
 Peak heart rate, bpm151±25
 Peak oxygen uptake, mL/kg/min19.7±7
 Peak oxygen uptake as percentage of expected value, %69±22
Right-sided cardiac catheterisation (97 patients)
 Right atrial pressure, mm Hg6 (4–10)
 Mean pulmonary artery pressure, mm Hg24±10
 Pulmonary capillary wedge pressure, mm Hg15±8
 Cardiac output, L/min4.9±1.5
24 h ECG (89 patients)
 Average heart rate, bpm76±13
 Minimum heart rate, bpm49±10
 Maximum heart rate, bpm142±28
 Ventricular tachycardia, n (%)25 (28)
  • Values are presented as mean±SD or median (IQR) as appropriate.