Table 1

Demographic and clinical data of tested and propensity score-matched postheart surgery population and healthy controls in the LGC trial

Tested populationPropensity score-matched population
Tested—post heart surgery population (N=361)Healthy controls (N=215)p ValueTested—post heart surgery population (N=167)Healthy controls (N=167)p Value
Caucasian race*343 (95.01)211 (98.14)0.058162 (97.01)164 (98.20)0.474
Exclusive European*330 (91.41)201 (93.49)0.369160 (95.81)156 (93.41)0.332
Exclusive Dutch language*296 (81.99)186 (86.51)0.155144 (86.23)142 (85.03)0.755
Male sex*205 (56.79)93 (43.26)0.00181 (48.50)81 (48.50)1.000
Age at randomisation, years†0.76 (0.22–4.1)NANA2.11 (0.34–4.77)NANA
Type of congenital heart disease*
 Obstructive pathology79 (21.88)NANA37 (22.15)NANA
 Left-right shunt121 (33.51)NANA60 (35.92)NANA
 Cyanotic and not univentricular122 (33.79)NANA59 (35.32)NANA
 Cyanotic and univentricular70 (19.39)NANA27 (16.16)NANA
 Other11 (3.04)NANA5 (2.99)NANA
RACHS classification*
 1 or 2168 (47.72)NANA79 (48.17)NANA
 3 or 4175 (49.71)NANA84 (51.21)NANA
 5 or 69 (2.55)NANA1 (0.60)NANA
Syndrome, at randomisation*69 (19.11)16 (7.44)<0.00120 (11.98)16 (9.58)0.480
PELOD first 24 h in ICU†11 (2–12)NANA11 (2–12)NANA
Socioeconomic status score35 (24–48.5)42.5 (29–54)<0.00139.5 (29–50)39.5 (29–52.5)0.455
At follow-up†
 Height, cm107 (103–126)122 (108–151)<0.001116 (104–131)117 (107–139)0.069
 Weight, kg18 (15–24)22 (18–40)<0.00120 (16–29)21 (18–34)0.072
 Head circumference, cm50.7 (49.2–52.5)52 (50.8–54)<0.00151 (49.5–53)51.8 (50.5–53.4)0.001
 Age, year4.67 (4.14–7.93)6.75 (4.68–11.56)<0.0016.02 (4.21–8.78)5.91 (4.58–9.07)0.359
  • *Numbers and percentages.

  • †Median (IQR).

  • ICU, intensive care unit; LGC, Leuven glucose control; NA, not applicable; PELOD, paediatric logistic organ dysfunction;43 RACHS, risk adjustment for congenital heart surgery.42