Table 1

Risk factors included in the standard 10-year Framingham and QRISK2 cardiovascular risk prediction algorithms

Risk factorsFramingham risk factorsQRISK2 risk factors
Age (years)
Gender (male/female)
Systolic blood pressure (mm  Hg)
Blood pressure treatment (yes/no)
Total cholesterol (mmol/L)
HDL cholesterol (mmol/L)
Total cholesterol/HDL ratio
Body mass index (kg/m2)
Diabetes (yes/no)
Family history of CHD <60 years (yes/no)
Chronic kidney disease (yes/no)
Atrial fibrillation (yes/no)
Rheumatoid arthritis (yes/no)
Smoking (yes/no)
Ethnicity (Caucasian/non-Caucasian)
Townsend score (quintiles)
AST/ALT ratio*
  • *Novel marker.

  • ALT, alanine transaminase; AST, aspartate transaminase; CHD, coronary heart disease; HDL, high-density lipoprotein.