Risk factors included in the standard 10-year Framingham and QRISK2 cardiovascular risk prediction algorithms
| Risk factors | Framingham risk factors | QRISK2 risk factors |
|---|---|---|
| Age (years) | ✓ | ✓ |
| Gender (male/female) | ✓ | ✓ |
| Systolic blood pressure (mm Hg) | ✓ | ✓ |
| Blood pressure treatment (yes/no) | ✓ | |
| Total cholesterol (mmol/L) | ✓ | |
| HDL cholesterol (mmol/L) | ✓ | ✓ |
| Total cholesterol/HDL ratio | ✓ | |
| Body mass index (kg/m2) | ✓ | |
| Diabetes (yes/no) | ✓ | ✓ |
| Family history of CHD <60 years (yes/no) | ✓ | |
| Chronic kidney disease (yes/no) | ✓ | |
| Atrial fibrillation (yes/no) | ✓ | |
| Rheumatoid arthritis (yes/no) | ✓ | |
| Smoking (yes/no) | ✓ | ✓ |
| Ethnicity (Caucasian/non-Caucasian) | ✓ | |
| Townsend score (quintiles) | ✓ | |
| AST/ALT ratio* |
*Novel marker.
ALT, alanine transaminase; AST, aspartate transaminase; CHD, coronary heart disease; HDL, high-density lipoprotein.