Table 3

Comparison of RAND-36 HRQOL scores between the UCORBIO cohort and the general Dutch population, stratified by gender

	Men						Women
Domains of RAND-36	Dutch population N=372	UCORBIO	Valid N	Δ Dutch population—UCORBIO	t Value	p Value	Dutch population N=691	UCORBIO	Valid N	Δ Dutch population—UCORBIO	t Value	p Value	Difference in Δ between genders
Physical functioning	84.5±22.3	70.9±26.1	993	−13.6	8.91	<0.001	80.7±23.6	55.3±28.4	389	−25.4	15.76	<0.001	−11.8
Social functioning	88.4±19.6	72.7±27.0	1004	−15.7	10.26	<0.001	86.1±20.9	61.2±29.5	397	−24.9	16.21	<0.001	−9.2
Physical role limitations	81.5±33.6	56.2±44.4	978	−25.3	9.96	<0.001	78.3±36.5	39.6±43.7	375	−38.7	15.40	<0.001	−13.4
Emotional role limitations	87.3±29.3	80.5±35.9	969	−6.8	3.26	0.011	82.5±33.5	72.1±41.0	365	−10.4	4.43	<0.001	−3.7
Mental functioning	79.4±17.3	76.7±16.7	998	−2.7	2.64	0.009	75.5±18.9	69.7±19.4	388	−5.8	4.79	<0.001	−3.1
Vitality	69.5±20.5	60.0±21.2	998	−9.5	7.44	<0.001	66.3±19.6	51.0±20.8	390	−15.3	12.05	<0.001	−5.8
Pain	83.2±23.8	76.4±26.5	1001	−6.8	4.34	<0.001	80.0±25.4	68.7±28.9	389	−11.3	6.67	<0.001	−4.5
General health	71.4±23.3	56.9±21.4	997	−14.5	10.88	<0.001	71.5±21.8	50.3±20.2	389	−21.2	15.75	<0.001	−6.7
Health change	52.6±18.3	46.1±26.4	1003	−6.5	4.37	<0.001	53.4±19.6	44.9±29.1	393	−8.5	5.73	<0.001	−2.0

All HRQOL scores are displayed as mean scores±SD. t Values and p values are reported for gender-specific differences between our cohort and the general population. The rightmost column gives the differences between Δ (difference between the general population and the UCORBIO cohort) of women and men, which is more negative in women in all nine domains of the RAND-36 questionnaire.
HRQOL, health-related quality of life; UCORBIO, Utrecht Coronary Biobank.