Atenolol and metoprolol versus carvedilol
| Outcome | Carvedilol | Atenolol | Metoprolol |
|---|---|---|---|
| Worsens lipids | No | Yes | Yes |
| Worsens glycaemic control | No | Yes | Yes |
| Mainly lowers BP through reductions in vasodilation versus cardiac output | Yes | No | No |
| Higher risk of microalbuminuria | No | No direct comparison | Yes |
| Increases weight | No | No direct comparison | Yes |
| Lower risk of mortality in patients with systolic HF and AMI | Yes | No | No |
AMI, acute myocardial infarction; BP, blood pressure; HF, heart failure.