Table 7

Performance of ICE risk models including traditional risk factors with and without hsCRP

C-index(95% CI)p ValueNRI(95% CI)IDI(95% CI)p Value
Basic model0.65(0.34 to 0.96)
Basic model+baseline hsCRP and 1-year changes0.68(0.33 to 1.03)<0.050.26(0.02 to 0.39)0.01(−0.01 to 0.04)0.4
  • Basic model: age, sex, heart rate, white cell count, tobacco and treatment group.

  • hsCRP, high-sensitivity C reactive protein; ICE, ischaemic cardiovascular event; IDI, integrated discrimination improvement; NRI, net reclassification improvement.