Table 5

Ischaemic cardiovascular event rates and HRs according to quartiles of baseline hsCRP in the whole cohort as well as in patients with increasing or decreasing hsCRP

Baseline hsCRPOne-year changes in hsCRP from baseline
 IncreaseDecrease
Quartiles of baseline hsCRPNHREvents per 1000 patient-yearsNHREvents per 1000 patient-yearsNHREvents per 1000 patient-years
1st quartile422129171137231121
2nd quartile4121.64 (1.15 to 2.33)*501431.61 (0.97 to 2.67)642321.74 (1.01 to 3.02)*37
3rd quartile3881.54 (1.08 to 2.22)*48851.47 (0.81 to 2.66)582581.75 (1.02 to 2.99)*38
4th quartile3961.73 (1.21 to 2.46)*52742.13 (1.22 to 3.71)*852801.77 (1.04 to 3.01)*37
1st–3rd quartile12221.24 (0.96 to 1.61)3991.62 (1.03 to 2.55)7211.18 (0.82 to 1.69)
  • *p<0.05.

  • hsCRP, high-sensitivity C reactive protein.