Pooled HR estimates for mutually adjusted risk variables
| Pooled HR | 95% CI | I2 | Study (n)* | Q-χ2 | Q-p value | Egger’s test | Trim-fill HR (95%CI) | |
|---|---|---|---|---|---|---|---|---|
| BMI (5 kg/m2) | 1.15 | 1.06 to 1.25 | 89.8 | 5 | 39.34 | <0.001 | 0.039 | 1.06 (0.96 to 1.16) |
| Gender (male) | 1.52 | 1.24 to 1.87 | 71.5 | 5 | 14.05 | 0.007 | 0.107 | 1.27 (1.03 to 1.56) |
| Smoker (yes) | 1.60 | 1.45 to 1.77 | 0.0 | 5 | 2.69 | 0.611 | 0.783 | 1.60 (1.45 to 1.77) |
| HTN (yes) | 1.61 | 1.33 to 1.96 | 64.1 | 5 | 11.14 | 0.025 | 0.358 | 1.41 (1.15 to 1.73) |
| Age (10 years) | 1.80 | 1.13 to 2.87 | 99.1 | 4 | 331.4 | <0.001 | 0.64 | 2.41 (1.49 to 3.91) |
| DM (yes) | 2.00 | 1.68 to 2.38 | 50.6 | 6 | 10.12 | 0.072 | 0.841 | 2.00 (1.68 to 2.38) |
| CAD (yes) | 2.94 | 1.36 to 6.33 | 97.7 | 6 | 212.6 | <0.001 | 0.583 | 6.71 (2.69 to 16.74) |
*Number of studies included in estimates for each listed risk factor.
BMI, body mass index; CAD, coronary artery disease; DM, diabetes mellitus; HTN, hypertension.
Columns in bold correspond to pooled HR (95%CI) to differentiate from the Trim-fill HR (95%CI) in the same table. The latter is obtained from Duval and Tweedie's method to check for publication bias.