Cox regression models predicting major cardiovascular and ischaemic events
| Variable | Cox regression model predicting major cardiovascular events | p Value | Cox regression model predicting ischaemic events | p Value |
|---|---|---|---|---|
| Baseline hsCRP (mg/L) | 1.1 (1.04–1.17) | 0.002 | 1.1 (1.00–1.20) | 0.043 |
| Increase in hsCRP (mg/L) | 1.17 (1.1–1.24) | <0.001 | 1.19 (1.12–1.25) | <0.001 |
| Hypertension | 2.12 (1.23–3.67) | 0.007 | ||
| Treatment allocation | 0.91 (0.75–1.1) | 0.99 | 0.87 (0.67–1.13) | 0.283 |
| Gender | 1.01 (1–1.02) | 0.33 | 0.68 (0.52–0.89) | 0.005 |
| Age | 1.01 (1–1.02) | 0.12 | 1.05 (1.03–1.07) | <0.001 |
| Heart rate (beats/min) | 1.01 (1–1.02) | 0.01 | ||
| WCC (109/L) | 1.12 (1.03–1.22) | 0.010 | ||
| Univariate (unadjusted) | ||||
| Baseline hsCRP (mg/L) | 1.06 (1.01–1.12)* | 0.021 | 1.13 (1.06–1.21)** | <0.001 |
| Increase in hsCRP (mg/L) | 1.12 (1.06–1.19)** | <0.001 | 1.19 (1.1–1.29)** | <0.001 |
*p<0.05; **p<0.001.
hsCRP, high-sensitivity C reactive protein; WCC, white cell count.