Table 3

Inflammatory response following diagnostic angiography and percutaneous coronary angiography

0 h†6 h24 h48 h72 h168 hANOVA
Angiography
 Leucocytes (×109/L)6.7±0.56.9±0.77.1±0.56.9±0.67.2±0.66.3±0.70.24
 Neutrophils (×109/L)4.1±0.44.1±0.44.4±0.44.1±0.34.4±0.44.1±0.40.57
 Lymphocytes (×109/L)1.7±0.22.0±0.31.8±0.21.9±0.31.9±0.31.7±0.30.07
 Monocytes (×109/L)0.56±0.030.59±0.060.59±0.050.58±0.050.58±0.040.56±0.050.93
 CRP (mg/L)1.2 (0.6–3.3)1.3 (0.6–2.9)1.5 (0.8–2.8)1.4 (0.7–4.0)1.6 (0.8–4.1)0.97
 VEGF-A (pg/L)76±1354±1069±968±879±130.16
PCI
 Leucocytes (×109/L)6.2±0.26.8±0.37.2±0.3*7.0±0.4*6.7±0.36.5±0.30.04
 Neutrophils (×109/L)3.8±0.24.2±0.34.7±0.2*4.3±0.34.0±0.23.8±0.30.04
 Lymphocytes (×109/L)1.8±0.11.9±0.11.7±0.21.9±0.11.9±0.11.8±0.10.41
 Monocytes (×109/L)0.49±0.020.54±0.040.54±0.030.54±0.030.51±0.030.48±0.040.14
 CRP (mg/L)1.0 (0.6–2.3)1.3 (0.8–2.4)2.6 (1.0–4.5)*4.0 (1.3–8.3)**2.0 (0.9–3.6)0.002
 VEGF-A (pg/L)72±857±557±556±550±50.16
  • Data are expressed as median and IQR or mean±SE of the mean. Statistical analyses are performed using repeated measures ANOVA (Friedman's test for non-parametric data) and Bonferroni's or Dunn's Multiple comparison test, where appropriate. Comparisons between time points are made using a paired Student's t test or Wilcoxon test, where appropriate.

  • *p<0.05 and **p=0.001 for preprocedure versus time point.

  • †Between group baseline comparison was made for each variable using a Mann-Whitney or unpaired Student t test, where appropriate.

  • ANOVA, analysis of variance; CRP, C reactive protein; PCI, percutaneous coronary intervention; VEGF-A, vascular endothelial growth factor-A.