Table 2

Cox proportional hazard risk model for primary end point (MACE) and secondary end point (revascularisation rate)

MACE
HR (95% CI)
p ValueCoronary revascularisation
HR (95% CI)
p Value
Smoker1.41 (0.29 to 6.92)0.671.31 (0.66 to 2.62)0.45
HT2.91 (0.35 to 24.70)0.331.91 (0.86 to 4.23)0.11
+FH0.81 (0.39 to 1.69)0.57
Cholesterol1.02 (0.66 to 1.40)0.941.26 (0.54 to 2.94)0.60
DM1.79 (0.29 to 11.17)0.541.46 (0.61 to 3.50)0.40
CCS
 ≥105.79 (0.70 to 47.59)0.105.05 (2.12 to 12.05)<0.001
 ≥1003.93 (0.89 to 17.42)0.086.01 (3.03 to 11.92)<0.0001
 ≥4005.57 (1.26 to 24.70)<0.05*3.90 (1.99 to 7.65)<0.0001
CT
 <50%2.87 (0.69 to 11.93)0.150.25 (0.06 to 1.03)0.06
 50–70%0.32 (0.04 to 2.32)0.26
 >70%3.40 (0.85 to 13.51)0.0827.92 (9.94 to 78.43)<0.0001*
SIS
 ≥11.33 (0.29 to 6.15)p=0.723.65 (1.9 to 7.0)p<0.0001*
 ≥56.50 (1.19 to 16.02)p<0.05*7.13 (2.2 to 23.1)p<0.0001*
ncSIS
 ≥11.27 (0.23 to 5.05)p=0.742.36 (1.20 to 4.63)p<0.01*
 ≥55.75 (0.69 to 47.94)p=0.111.82 (0.43 to 747)p=0.42
  • *Statistical significance.

  • +FH, positive family history; CAD, coronary artery disease; CCS, coronary calcium score; DM, diabetes mellitus; HT, arterial hypertension; ncSIS, non-calcified plaque segment involvement score; SIS, segment involvement score (reflecting total plaque burden).