Heavy drinking group, IHD end point | Reference group | Number of studies | Number of events* | Number of chronic heavy drinkers | Relative risk | 95% CI | p Value† | I2 (%) |
---|---|---|---|---|---|---|---|---|
Chronic heavy drinking (population samples) | ||||||||
Incidence | Lifetime abstainers | 11 | 954 | 35 756 | 1.04 | 0.83 to 1.31 | 0.016 | 54 |
Mortality | Lifetime abstainers | 5 | 618 | 34 182 | 1.00 | 0.74 to 1.36 | 0.026 | 64 |
Morbidity | Lifetime abstainers | 3 | 299 | 471 | 1.13 | 0.78 to 1.63 | 0.97 | 0 |
Incidence | Current abstainers | 14 | 1268 | 50 805 | 0.83 | 0.70 to 0.98 | <0.001 | 73 |
Mortality | Current abstainers | 9 | 853 | 46 450 | 0.85 | 0.67 to 1.08 | <0.001 | 74 |
Morbidity | Current abstainers | 2 | 193 | 884 | 0.78 | 0.21 to 2.90 | 0.006 | 87 |
Patients with AUD (clinical samples) | ||||||||
Mortality | General population | 9 | 761 | 18 758 | 1.62 | 1.34 to 1.95 | <0.001 | 81 |
See Methods section for definitions of chronic heavy drinking groups.
*In chronic heavy drinking groups.
†For heterogeneity (Cochran's Q).