hs-cTnT pattern | |||
---|---|---|---|
Variable | Stable (n=12) | Dynamic (n=53) | p Value |
Demographics | |||
Age, years (SD) | 78.9 (6.5) | 70.3 (8.7) | 0.002 |
Female, n (%) | 4 (33%) | 24 (45%) | 0.531 |
Medical history | |||
Coronary artery disease, n (%) | 5 (42%) | 9 (17%) | 0.060 |
Left heart failure, n (%) | 3 (25%) | 5 (9.4%) | 0.158 |
Right heart failure, n (%) | 0 | 3 (5.7%) | 0.399 |
FEV1, L (SD)* | 0.88 (0.39) | 0.91 (0.47) | 0.845 |
FEV1/FVC ratio, % (SD)* | 44 (11) | 46 (14) | 0.719 |
Current smokers, n (%) | 3 (25%) | 19 (36%) | 0.737 |
Prior smokers, n (%) | 8 (67%) | 27 (51%) | 0.359 |
Never smokers, n (%) | 0 | 0 | – |
Laboratory tests | |||
Hb, g/dL, mean (SD) | 12.9 (1.5) | 14.2 (1.6) | 0.016 |
Creatinine, µg/L, mean (SD) | 82 (36) | 77 (41) | 0.493 |
eGFR, mL/min/1.73 m2, mean (SD) | 85 (38) | 93 (38) | 0.510 |
First hs-cTnT, ng/L, median (IQR) | 38.2 (28.0–53.7) | 31.2 (17.8–60.3) | 0.577 |
Highest hs-cTnT, ng/L, median (IQR) | 38.9 (28.8–53.7) | 39.4 (21.9–71.1) | 0.987 |
NT-proBNP tertile | 0.073 | ||
1 (<283 pg/mL), n (%) | 1 (8.3%) | 20 (38%) | |
2 (283–1181 pg/mL), n (%) | 4 (33%) | 18 (34%) | |
3 (≥1181 pg/mL), n (%) | 8 (58%) | 15 (28%) | |
ECG analysis | |||
Current iscahemia, n (%) | 5 (42%) | 19 (36%) | 0.706 |
Prior myocardial infarction, n (%) | 3 (25%) | 7 (13%) | 0.376 |
Atrial fibrillation, n (%) | 2 (17%) | 3 (5.7%) | 0.227 |
P pulmonale | 4 (33%) | 15 (28%) | 0.735 |
Right ventricular hypertrophy | 1 (8.3%) | 8 (15%) | 0.999 |
The table includes variables that differed with a p value <0.20. Gender, lung and kidney function, smoking status, chest pain and ECG analyses are also included for characterisation of the cohort.
*Spirometry missing in seven patients, n=10 and 48.
AECOPD, acute exacerbation of chronic obstructive pulmonary disease; BNP, B-type natriuretic peptide; eGFR, epidermal growth factor receptor; FEV, forced expiratory volume in 1 s; FVC, forced vital capacity; Hb, haemoglobin.