RT Journal Article
SR Electronic
T1 Coronary endothelial dysfunction: from pathogenesis to clinical implications
JF Open Heart
JO Open Heart
FD British Cardiovascular Society
SP e002200
DO 10.1136/openhrt-2022-002200
VO 9
IS 2
A1 Bockus, Lee
A1 Kim, Francis
YR 2022
UL http://openheart.bmj.com/content/9/2/e002200.abstract
AB Endothelial dysfunction (ED) has a substantial role in the pathogenesis of atherosclerosis and other vascular diseases. Multiple risk factors, including smoking, hyperlipiadaemia and diabetes, can have associated ED, which is correlated with cardiac events. Measurement of coronary artery endothelial function requires the use of invasive techniques to assess both epicardial coronary artery and microvascular beds. Peripheral vascular techniques and endothelial biomarkers can be used to indirectly assess coronary ED. In this review of coronary artery ED, we discuss the current state of the field, the techniques used to measure ED and its clinical implications.Data sharing not applicable as no datasets generated and/or analysed for this study.