TY - JOUR T1 - Early invasive strategy (< 24 hours) in patients with acute coronary syndromes: weighing the evidence JF - Open Heart JO - Open Heart DO - 10.1136/openhrt-2022-001997 VL - 9 IS - 1 SP - e001997 AU - Samuele Nanni AU - Tullio Palmerini AU - Anna Corsini AU - Franco Semprini AU - Nazzareno Galiè Y1 - 2022/03/01 UR - http://openheart.bmj.com/content/9/1/e001997.abstract N2 - The recent 2020 European Society of Cardiology Guidelines for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation (NSTE) recommend an early (<24 hours) invasive strategy with class of recommendation I, level of evidence A for the following groups of patients: all patients with NSTE myocardial infarction (NSTEMI) according to the diagnostic algorithm proposed by the guidelines, patients with dynamic or presumably new contiguous ST/T-segment changes suggesting ongoing ischaemia, patients with transient ST-segment elevation and patients with a Global Registry of Acute Coronary Events (GRACE) risk score >140.This recommendation thus comprises a heterogeneous population including patients at very high risk, such as those with a GRACE score >140, as well as those with a less defined risk profile, such as … ER -