TY - JOUR T1 - Associations between physical activity, sedentary behaviour and left ventricular structure and function from the Echocardiographic Study of Latinos (ECHO-SOL) JF - Open Heart JO - Open Heart DO - 10.1136/openhrt-2021-001647 VL - 8 IS - 2 SP - e001647 AU - Andrew E Berdy AU - Bharathi Upadhya AU - Sonia Ponce AU - Katrina Swett AU - Richard B Stacey AU - Robert Kaplan AU - Priscilla M Vasquez AU - Qibin Qi AU - Neil Schneiderman AU - Barry E Hurwitz AU - Martha L Daviglus AU - Mayank Kansal AU - Kelly R Evenson AU - Carlos J Rodriguez Y1 - 2021/07/01 UR - http://openheart.bmj.com/content/8/2/e001647.abstract N2 - Objective The cross-sectional association between accelerometer-measured physical activity (PA), sedentary behaviour (SB) and cardiac structure and function is less well described. This study’s primary aim was to compare echocardiographic measures of cardiac structure and function with accelerometer measured PA and SB.Methods Participants included 1206 self-identified Hispanic/Latino men and women, age 45–74 years, from the Echocardiographic Study of Latinos. Standard echocardiographic measures included M-mode, two-dimensional, spectral, tissue Doppler and myocardial strain. Participants wore an Actical accelerometer at the hip for 1 week.Results The mean±SE age for the cohort was 56±0.4 years, 57% were women. Average moderate to vigorous PA (MVPA) was 21±1.1 min/day, light PA was 217±4.2 min/day and SB was 737±8.1 min/day. Both higher levels of light PA and MVPA (min/day) were associated with lower left ventricular (LV) mass index (LVMI)/end-diastolic volume and a lower E/e′ ratio. Higher levels of MVPA (min/day) were associated with better right ventricular systolic function. Higher levels of SB were associated with increased LVMI. In a multivariable linear regression model adjusted for demographics and cardiovascular disease modifiable factors, every 10 additional min/day of light PA was associated with a 0.03 mL/m2 increase in left atrial volume index (LAVI) (p<0.01) and a 0.004 cm increase in tricuspid annular plane systolic excursion (p<0.01); every 10 additional min/day of MVPA was associated with a 0.18 mL/m2 increase in LAVI (p<0.01) and a 0.24% improvement in global circumferential strain (p<0.01).Conclusions Our findings highlight the potential positive association between the MVPA and light PA on cardiac structure and function.Data may be obtained from a third party and are not publicly available. All HCHS-SOL data will be included in a limited access database that will be available to the larger scientific public as part of the main HCHS-SOL study database for public use. It will be encouraged that all use of data and publications from ancillary studies invite the participation of the ancillary study PI and coinvestigators. ER -