RT Journal Article SR Electronic T1 Effects of lockdown on acute coronary syndrome incidence in an area without community transmission of COVID-19 JF Open Heart JO Open Heart FD British Cardiovascular Society SP e001692 DO 10.1136/openhrt-2021-001692 VO 8 IS 1 A1 David Ferreira A1 Simon Graffen A1 Brendan Watkins A1 Bridie Peters A1 Geok Jim Lim A1 Harish Kamalanathan A1 James Leitch A1 Aaron Sverdlov A1 Nicholas Collins A1 Andrew Boyle A1 Allan Davies YR 2021 UL http://openheart.bmj.com/content/8/1/e001692.abstract AB Objective To assess the changes in cardiac hospitalisations, acute coronary syndromes (ACS) and out-of-hospital cardiac arrest (OOHCA) during COVID-19 isolation compared with prior time periods in an area of low COVID-19 disease incidence.Methods Review of all cardiology admissions, non-ST segment elevation myocardial infarction (NSTEMI), ST-segment elevation myocardial infarction (STEMI) requiring urgent catheter laboratory activation and OOHCA. The 10-week period of government-imposed social isolation (23 March–31 May 2020) was compared with the same period in 2018, 2019 and a 10-week period prior to social isolation (6 January–15 March 2020). Incidence rate ratios were calculated. Symptom to balloon time was also compared for those requiring catheterisation laboratory activation for STEMI.Results The incidence of COVID-19 in the health district was 0.14 per 100 000 per day during the isolation period. There was a significant reduction in cardiology hospitalisations, NSTEMI and STEMI presentations without changes in OOHCA or symptom to balloon time for STEMI.Conclusions We observed a significant decline in cardiology presentations during social isolation without widespread COVID-19 disease. This provides further evidence for the important influence of social and behavioural factors on coronary event rates.All data relevant to the study are included in the article.