RT Journal Article
SR Electronic
T1 Coronary artery calcium progression after coronary artery bypass grafting surgery
JF Open Heart
JO Open Heart
FD British Cardiovascular Society
SP e001684
DO 10.1136/openhrt-2021-001684
VO 8
IS 1
A1 Rami M Abazid
A1 Jonathan G Romsa
A1 Cigdem Akincioglu
A1 James C Warrington
A1 Yves Bureau
A1 Bob Kiaii
A1 William C Vezina
YR 2021
UL http://openheart.bmj.com/content/8/1/e001684.abstract
AB Objectives Accelerated atherosclerosis is a well-established phenomenon after coronary artery bypass grafting surgery (CABG). In this study, we analysed coronary artery calcium (CCS) progression after CABG.Methods We retrospectively measured the CCS Agatston score (AS), volume score (VS) and mass score (MS) of 39 patients before and after CABG. The annualised CCS change and annualised CCS percent change of each coronary artery, coronary artery segments proximal and distal to anastomosis were analysed.Results Mean age at the time of the surgery was 59.8±8.5 years. Follow-up period between the first and second CT scans was 6.7±2.8 (range, 1.1–12.8) years. Annualised CCS percent change (AS, VS and MS) of the coronary segments proximal-to-anastomosis did not differ from that of the non-grafted coronary arteries as follow: segments proximal-to-anastomosis: median (Q1–Q3) 12.8 (5.0–37.4), 13.7 (6.1–41.1) and 14.9 (5.4–53.7), left main coronary artery 12.6 (7.4–43.8), 22.0 (8.1–44.4) and 18.2 (7.3–57.4), non-grafted left circumflex artery: 13.5 (4.4–38.1), 10.5 (2.9–45.2) and 11.5 (7.1–47.9) and non-grafted right coronary artery: 31.4 (14.4–74.5), 25.2 (16.7–62.0) and 31.3 (23.8–85.6), respectively. Likewise, annualised percent change (AS, VS and MS) was similar between the native coronary arteries. Multivariate regression analysis showed that diabetes mellitus was the only predictor of annualised percent progression of the total CCS of >15% (HR, 8.12; 95% CI, 1.05 to 26.6; p=0.04).Conclusion The CCS post-CABG did not follow an accelerated progression process. Among coronary artery disease risk factors, diabetes mellitus is the only predictor of annualised CCS percent progression of >15% post-CABG.Data are available upon reasonable request.