RT Journal Article SR Electronic T1 Effect of procedural refinement of transfemoral transcatheter aortic valve implantation on outcomes and costs: a single-centre retrospective study JF Open Heart JO Open Heart FD British Cardiovascular Society SP e001064 DO 10.1136/openhrt-2019-001064 VO 6 IS 2 A1 Sangaraju, Sivasankar A1 Cox, Ian A1 Dalrymple-Hay, Malcolm A1 Lloyd, Clinton A1 Suresh, Venkatesan A1 Riches, Tania A1 Melhuish, Samantha A1 Asopa, Sanjay A1 Newcombe, Samantha A1 Deutsch, Cornelia A1 Bramlage, Peter YR 2019 UL http://openheart.bmj.com/content/6/2/e001064.abstract AB Objectives To determine the effect of introducing several procedural refinements of transfemoral transcatheter aortic valve implantation (TAVI) on clinical outcomes and costs.Design Retrospective analysis comparing two consecutive 1-year periods, before and after the introduction of procedural refinements.Setting Tertiary hospital aortic valve programme.Participants Consecutive patients undergoing transfemoral TAVI treated between April 2014 and August 2015 using the initial setup (n=70; control group) or between September 2015 and August 2016 after the introduction of procedural refinements (n=89).Interventions Introduction of conscious sedation, percutaneous access and closure, omission of transoesophageal echocardiography during the procedure, and an early discharge procedure.Outcome measures Procedural characteristics, complications and outcomes; length of stay in intensive care unit (ICU) and hospital; hospital-related direct costs associated with TAVI.Results There were no statistically significant differences in the incidence of complications or mortality between the two groups. The mean length of stay in the ICU was significantly shorter in the procedural-refinement group compared with the control group (5.1 vs 57.2 hours, p<0.001), as was the mean length of hospital stay (4.7 vs 6.6 days, p<0.001). The total cost per TAVI procedure was significantly lower, by £3580, in the procedural-refinement group (p<0.001). This was largely driven by lower ICU costs.Conclusions Among patients undergoing transfemoral TAVI, procedural refinement facilitated a shorter stay in ICU and earlier discharge from hospital and was cost saving compared with the previous setup.