PT - JOURNAL ARTICLE AU - Sangaraju, Sivasankar AU - Cox, Ian AU - Dalrymple-Hay, Malcolm AU - Lloyd, Clinton AU - Suresh, Venkatesan AU - Riches, Tania AU - Melhuish, Samantha AU - Asopa, Sanjay AU - Newcombe, Samantha AU - Deutsch, Cornelia AU - Bramlage, Peter TI - Effect of procedural refinement of transfemoral transcatheter aortic valve implantation on outcomes and costs: a single-centre retrospective study AID - 10.1136/openhrt-2019-001064 DP - 2019 Sep 01 TA - Open Heart PG - e001064 VI - 6 IP - 2 4099 - http://openheart.bmj.com/content/6/2/e001064.short 4100 - http://openheart.bmj.com/content/6/2/e001064.full SO - Open Heart2019 Sep 01; 6 AB - Objectives To determine the effect of introducing several procedural refinements of transfemoral transcatheter aortic valve implantation (TAVI) on clinical outcomes and costs.Design Retrospective analysis comparing two consecutive 1-year periods, before and after the introduction of procedural refinements.Setting Tertiary hospital aortic valve programme.Participants Consecutive patients undergoing transfemoral TAVI treated between April 2014 and August 2015 using the initial setup (n=70; control group) or between September 2015 and August 2016 after the introduction of procedural refinements (n=89).Interventions Introduction of conscious sedation, percutaneous access and closure, omission of transoesophageal echocardiography during the procedure, and an early discharge procedure.Outcome measures Procedural characteristics, complications and outcomes; length of stay in intensive care unit (ICU) and hospital; hospital-related direct costs associated with TAVI.Results There were no statistically significant differences in the incidence of complications or mortality between the two groups. The mean length of stay in the ICU was significantly shorter in the procedural-refinement group compared with the control group (5.1 vs 57.2 hours, p<0.001), as was the mean length of hospital stay (4.7 vs 6.6 days, p<0.001). The total cost per TAVI procedure was significantly lower, by £3580, in the procedural-refinement group (p<0.001). This was largely driven by lower ICU costs.Conclusions Among patients undergoing transfemoral TAVI, procedural refinement facilitated a shorter stay in ICU and earlier discharge from hospital and was cost saving compared with the previous setup.