PT - JOURNAL ARTICLE AU - Khaled Alfakih AU - Jonathan Byrne AU - Mark Monaghan TI - CT coronary angiography: a paradigm shift for functional imaging tests AID - 10.1136/openhrt-2017-000754 DP - 2018 Mar 01 TA - Open Heart PG - e000754 VI - 5 IP - 1 4099 - http://openheart.bmj.com/content/5/1/e000754.short 4100 - http://openheart.bmj.com/content/5/1/e000754.full SO - Open Heart2018 Mar 01; 5 AB - The UK National Institute for Health and Care Excellence (NICE) have just updated their guideline on new-onset stable chest pain, recommending that all patients should be investigated with a CT coronary angiography (CTCA). In a separate guideline, NICE recommended CT fractional flow reserve (CT-FFR), to assess coronary stenoses, found on CTCA, stating that this would reduce the need for invasive coronary angiography and hence reduce cost. We discuss the evidence base for CT-FFR and emphasise that we already have established functional imaging tests, with extensive evidence base for efficacy and prognosis and that CT-FFR should be compared with this standard of care and not with the much more expensive and invasive fractional flow reserve undertaken during invasive coronary angiography.