RT Journal Article SR Electronic T1 Role of frailty assessment in patients undergoing cardiac interventions JF Open Heart JO Open Heart FD British Cardiovascular Society SP e000033 DO 10.1136/openhrt-2013-000033 VO 1 IS 1 A1 Rebecca Rowe A1 Javaid Iqbal A1 Rachel Murali-krishnan A1 Ayyaz Sultan A1 Rachel Orme A1 Norman Briffa A1 Martin Denvir A1 Julian Gunn YR 2014 UL http://openheart.bmj.com/content/1/1/e000033.abstract AB Average life expectancy is increasing in the western world resulting in a growing number of frail individuals with coronary heart disease, often associated with comorbidities. Decisions to proceed to invasive interventions in elderly frail patients is challenging because they may gain benefit, but are also at risk of procedure-related complications. Current risk scores designed to predict mortality in cardiac procedures are mainly based on clinical and angiographic factors, with limitations in the elderly because they are mainly derived from a middle-aged population, do not account for frailty and do not predict the impact of the procedure on quality of life which often matters more to elderly patients than mortality. Frailty assessment has emerged as a measure of biological age that correlates well with quality of life, hospital admissions and mortality. Potentially, the incorporation of frailty into current risk assessment models will cause a shift towards more appropriate care. The need for a more accurate method of risk stratification incorporating frailty, particularly for elderly patients is pressing. This article reviews the association between frailty and cardiovascular disease, the impact of frailty on outcomes of cardiac interventions and suggests ways in which frailty assessment could be incorporated into cardiology clinical practice.