Open Heart: 8 (1)

Editorial

Sex-based inequalities in contemporary UK hospital management of stable chest pain (2 June, 2021)
Mirvat Alasnag, Nouf Alanazi
Exercise prescription in young children with congenital heart disease: time for a change in culture (2 June, 2021)
Graham Stuart, Lynsey Forsythe
Perception is not reality when risk stratifying adults with congenital heart disease for COVID-19 (17 May, 2021)
Su Yuan, Erwin Oechslin
Exercise stress echocardiography: a great tool that can be adapted to the clinical question? (22 April, 2021)
Erwan Donal, Vasileios Panis, Wojciech Kosmala
A nutraceutical strategy for downregulating TGFβ signalling: prospects for prevention of fibrotic disorders, including post-COVID-19 pulmonary fibrosis (20 April, 2021)
James J DiNicolantonio, Mark F McCarty, Jorge Barroso-Aranda, Simon Assanga, Lidianys Maria Lewis Lujan, James H O'Keefe
Anti-inflammatory activity of ivermectin in late-stage COVID-19 may reflect activation of systemic glycine receptors (19 April, 2021)
James J DiNicolantonio, Jorge Barroso-Aranda, Mark F McCarty
Melatonin may decrease risk for and aid treatment of COVID-19 and other RNA viral infections (19 March, 2021)
James J DiNicolantonio, Mark McCarty, Jorge Barroso-Aranda

Aortic and vascular disease

Original research: Impaired coronary flow velocity reserve is associated with cardiovascular risk factors but not with angina symptoms (18 January, 2021)
Kira Bang Bove, Marie M Michelsen, Jakob Schroder, Hannah Elena Suhrs, Daria F Bechsgaard, Naja Dam Mygind, Ahmed Aziz, Jens Kastrup, Ida Gustafsson, Eva Prescott

Arrhythmias and sudden death

Original research: Patients with symptomatic permanent atrial fibrillation show quantitative signs of pain sensitisation (17 June, 2021)
Adam Jackson, Ole Frobert, Dennis Boye Larsen, Lars Arendt-Nielsen, Anna Björkenheim
Original research: Heart rate and adverse outcomes in patients with prevalent atrial fibrillation (21 April, 2021)
Giorgio Moschovitis, Linda S B Johnson, Steffen Blum, Stefanie Aeschbacher, Maria Luisa De Perna, Alberto Pagnamenta, Patrizia Assunta Mayer Melchiorre, Alexander P Benz, Richard Kobza, Marcello Di Valentino, Christine S Zuern, Angelo Auricchio, Giulio Conte, Nicolas Rodondi, Manuel R Blum, Juerg H Beer, Michael Kühne, Stefan Osswald, David Conen
Original research: Evaluation of the prognostic value of GDF-15, ABC-AF-bleeding score and ABC-AF-death score in patients with atrial fibrillation across different geographical areas (19 March, 2021)
Tymon Pol, Ziad Hijazi, Johan Lindbäck, John H Alexander, M Cecilia Bahit, Raffaele De Caterina, JW Eikelboom, Michael D Ezekowitz, Bernard J Gersh, Christopher B Granger, Elaine M Hylek, Renato Lopes, Agneta Siegbahn, Lars Wallentin
Original research: Economic value of insertable cardiac monitors in unexplained syncope in the United States (23 February, 2021)
Brad S Sutton, Sarah L Bermingham, Alexander Diamantopoulos, Sarah C Rosemas, Stelios I Tsintzos, Ying Xia, Matthew R Reynolds
Original research: Discovery of predictors of sudden cardiac arrest in diabetes: rationale and outline of the RESCUED (REcognition of Sudden Cardiac arrest vUlnErability in Diabetes) project (5 February, 2021)
Laura H van Dongen, Peter P Harms, Mark Hoogendoorn, Dominic S Zimmerman, Elisabeth M Lodder, Leen M 't Hart, Ron Herings, Henk C P M van Weert, Giel Nijpels, Karin M A Swart, Amber A van der Heijden, Marieke T Blom, Petra J Elders, Hanno L Tan
Original research: Territory-wide cohort study of Brugada syndrome in Hong Kong: predictors of long-term outcomes using random survival forests and non-negative matrix factorisation (5 February, 2021)
Sharen Lee, Jiandong Zhou, Ka Hou Christien Li, Keith Sai Kit Leung, Ishan Lakhani, Tong Liu, Ian Chi Kei Wong, Ngai Shing Mok, Chloe Mak, Kamalan Jeevaratnam, Qingpeng Zhang, Gary Tse
Proposed A₂C₂S₂-VASc score for predicting atrial fibrillation development in patients with atrial flutter
(29 January, 2021)
Yung-Lung Chen, Hui-Ting Wang, Huang-Chung Chen, Wen-Hao Liu, Shaur-Zheng Chong, Shu-Kai Hsueh, Chang-Ming Chung, Yu-Shen Lin
Original research: Algorithm for cavo-tricuspid isthmus flutter on surface ECGs: the ACTIONS study (27 January, 2021)
Daniel R Frisch, Eitan Frankel, Deanna Gill, Jad Al Danaf

Basic and translational research

Original research: Hospital admissions for stroke and bleeding in Hounslow following a quality improvement initiative (1 March, 2021)
Kam Ying Wong, Bethan Davies, Yewande Adeleke, Thomas Woodcock, Dionne Matthew, Sara Sekelj, Andi Orlowski, Bradley Porter, Sophia Hashmy, Ammu Mathew, Ron Grant, Agnes Kaba, Brigitte Unger-Graeber, Bruno Petrungaro, Jordan Wallace, Derek Bell, Martin R Cowie, Sadia Khan
Original research: Comparison of left ventricular rotational mechanics between term and extremely premature infants over the first week of age (27 January, 2021)
Aisling Smith, Neidin Bussmann, Phillip Levy, Orla Franklin, Naomi McCallion, Afif EL-Khuffash

Cardiac risk factors and prevention

Original research: Self-care practice among hypertensive patients in Ethiopia: systematic review and meta-analysis (21 May, 2021)
Degena Bahrey Tadesse, Hadgu Gerensea
Original research: Right atrium and cryptogenic ischaemic stroke in the young: a case–control study (18 May, 2021)
Pauli Pöyhönen, Jouni Kuusisto, Jani Pirinen, Heli Räty, Lauri Lehmonen, Riitta Paakkanen, Nicolas Martinez-Majander, Eva Gerdts, Jukka Putaala, Juha Sinisalo, Vesa Järvinen
Original research: Incremental prognostic value of visually estimated coronary artery calcium in patients undergoing positron emission tomography imaging (7 May, 2021)
Senthil Selvaraj, Muhammad Shoaib Khan, Mahesh K Vidula, Philip C Wiener, Alejandro E de Feria, Chaitanya Rojulpote, Sheela Krishnan, Ruth Tamrat, Howard Julien, Douglas Jacoby, Harold Litt, Daniel Pryma, Jacob Dubroff, Marie A Guerraty, Paco Bravo
Original research: Cardiovascular risk factors and autonomic indices in relation to fatal and non-fatal coronary events (20 April, 2021)
Christian Zambach, Artur Fedorowski, Yan Borné, Linda S B Johnson, Sofia Gerward, Viktor Hamrefors, Gunnar Engström
Original research: Mortality and high risk of major adverse events in patients with COVID-19 and history of cardiovascular disease (8 April, 2021)
Elena Tessitore, David Carballo, Antoine Poncet, Nils Perrin, Cedric Follonier, Benjamin Assouline, Sebastian Carballo, François Girardin, Francois Mach
Original research: COVID-19 and its impact on the cardiovascular system (15 March, 2021)
Saud Ahmed Khawaja, Poornima Mohan, Richard Jabbour, Theodora Bampouri, Gemma Bowsher, Ahmed M M Hassan, Farhan Huq, Lilit Baghdasaryan, Brian Wang, Amarjit Sethi, Sayan Sen, Ricardo Petraco, Neil Ruparelia, Sukhjinder Nijjer, Iqbal Malik, Rodney Foale, Michael Bellamy, Jaspal Kooner, Bushra Rana, Graham Cole, Nilesh Sutaria, Gajen Kanaganayagam, Petros Nihoyannopoulos, Kevin Fox, Carla Plymen, Punam Pabari, Luke Howard, Rachel Davies, Gulammehdi Haji, Francesco Lo Giudice, Prapa Kanagaratnam, Jon Anderson, Andrew Chukwuemeka, Ramzi Khamis, Amanda Varnava, Christopher S R Baker, Darrel Parthipan Francis, Perviz Asaria, Rasha Al-Lamee, Ghada W Mikhail
Original research: Ten-year follow-up of cardiac function and neural regulation in a group of amateur half-marathon runners (9 February, 2021)
Beatrice De Maria, Mariana de Oliveira Gois, Aparecida Maria Catai, Christian Marra, Daniela Lucini, Alberto Porta, Massimo Pagani, Laura Adelaide Dalla Vecchia
Original research: Prevalence and determinants of hypertension control among almost 100 000 treated adults in the UK (11 March, 2021)
Neo Tapela, Jennifer Collister, Lei Clifton, Iain Turnbull, Kazem Rahimi, David J Hunter
Original research: Incident hypertension in urban slums of central India: a prospective cohort study (18 January, 2021)
Abhijit P Pakhare, Anuja Lahiri, Neelesh Shrivastava, Ankur Joshi, Sagar Khadanga, Rajnish Joshi
Original research: CHARGE-AF in a national routine primary care electronic health records database in the Netherlands: validation for 5-year risk of atrial fibrillation and implications for patient selection in atrial fibrillation screening (18 January, 2021)
Jelle C L Himmelreich, Wim A M Lucassen, Ralf E Harskamp, Claire Aussems, Henk C P M van Weert, Mark M J Nielen

Cardiac surgery

Original research: Does postoperative cognitive decline after coronary bypass affect quality of life? (22 April, 2021)
Fredrike Blokzijl, Frederik Keus, Saskia Houterman, Willem Dieperink, Iwan C C van der Horst, Michiel F Reneman, Anthony R Absalom, Massimo A Mariani
Original research: Surgical treatment for infective endocarditis in the ageing society: a nationwide retrospective study in Japan (12 April, 2021)
Hiroyuki Kiriyama, Hidehiro Kaneko, Hidetaka Itoh, Tatsuya Kamon, Kojiro Morita, Taisuke Jo, Katsuhito Fujiu, Masao Daimon, Norifumi Takeda, Hiroyuki Morita, Hideo Yasunaga, Issei Komuro
Original research: Music intervention to relieve anxiety and pain in adults undergoing cardiac surgery: a systematic review and meta-analysis (25 January, 2021)
Ellaha Kakar, Ryan J Billar, Joost van Rosmalen, Markus Klimek, Johanna J M Takkenberg, Johannes Jeekel

Coronary artery disease

Original research: Effects of lockdown on acute coronary syndrome incidence in an area without community transmission of COVID-19 (21 June, 2021)
David Ferreira, Simon Graffen, Brendan Watkins, Bridie Peters, Geok Jim Lim, Harish Kamalanathan, James Leitch, Aaron Sverdlov, Nicholas Collins, Andrew Boyle, Allan Davies
Original research: Coronary artery calcium progression after coronary artery bypass grafting surgery (14 June, 2021)
Rami M Abazid, Jonathan G Romsa, Cigdem Akincioglu, James C Warrington, Yves Bureau, Bob Kiaii, William C Vezina
Original research: Assessment of stunned and viable myocardium using manganese-enhanced MRI (7 June, 2021)
Nick B Spath, Trisha Singh, Giorgos Papanastasiou, Andrew Baker, Rob J Janiczek, Gerry P McCann, Marc R Dweck, Lucy Kershaw, David E Newby, Scott Semple
Original research: Type 2 myocardial infarction and myocardial injury: eligibility for novel medical therapy to derisk clinical trials (2 June, 2021)
Robert Sykes, Michael Briscoe, Thomas Krysztofiak, Oliver Peck, Kenneth Mangion, Colin Berry
Original research: Diagnostic role of coronary CT angiography in paroxysmal or first diagnosed atrial fibrillation (18 May, 2021)
Dennis Rottländer, Martin Saal, Hubertus Degen, Miriel Gödde, Marc Horlitz, Michael Haude
Original research: Sex differences in mortality in stable patients undergoing vasodilator stress cardiovascular magnetic resonance (17 May, 2021)
Gema Miñana, Julio Núñez, Jose V Monmeneu, Maria P López-Lereu, Jose Gavara, Víctor Marcos-Garcés, Cesar Ríos-Navarro, Nerea Pérez, Elena de Dios, Agustín Fernández-Cisnal, Eduardo Núñez, Francisco J Chorro, Juan Sanchis, Vicente Bodi
Original research: Intensified lipid-lowering treatment with alirocumab in patients with coronary heart disease (17 May, 2021)
Daniel Steffens, Peter Bramlage, Julia Müller, Cornelia Dorn, W Dieter Paar, Celine Scheeff, Mario Kasner, U Rauch-Kröhnert
Original research: Use of historical high-sensitivity cardiac troponin T levels to rule out myocardial infarction (14 May, 2021)
Andreas Roos, Martin J Holzmann
Original research: Tocilizumab increases citrullinated histone 3 in non-ST segment elevation myocardial infarction (10 May, 2021)
Ragnhild Helseth, Ola Kleveland, Thor Ueland, Rune Wiseth, Jan Kristian Damas, Kaspar Broch, Annika Michelsen, Bjørn Bendz, Lars Gullestad, Pål Aukrust, Ingebjørg Seljeflot
Original research: Patient delay and benefit of timely reperfusion in ST-segment elevation myocardial infarction (6 May, 2021)
Karl Heinrich Scholz, Thomas Meyer, Björn Lengenfelder, Christian Vahlhaus, Jörn Tongers, Steffen Schnupp, Rainer Burckhard, Nicolas von Beckerath, Hans-Martin Grusnick, Andreas Jeron, Klaus Dieter Winter, Sebastian K G Maier, Michael Danner, Jürgen vom Dahl, Stefan Neef, Stefan Stefanow, Tim Friede
Original research: Assessing the severity of cardiovascular disease in 213 088 patients with coronary heart disease: a retrospective cohort study (20 April, 2021)
Salwa S Zghebi, Mamas A Mamas, Darren M Ashcroft, Martin K Rutter, Harm VanMarwijk, Chris Salisbury, Christian D Mallen, Caroline A Chew-Graham, Nadeem Qureshi, Stephen F Weng, Tim Holt, Iain Buchan, Niels Peek, Sally Giles, David Reeves, Evangelos Kontopantelis
Original research: Undiagnosed SARS-CoV-2 infection and outcome in patients with acute MI and no COVID-19 symptoms (2 April, 2021)
Zubair Akhtar, Fahmida Chowdhury, Mohammad Abdul Aleem, Probir Kumar Ghosh, Mahmudur Rahman, Mustafizur Rahman, Mohammad Enayet Hossain, Mariya Kibtiya Sumiya, A K M Monwarul Islam, Mir Jamal Uddin, C Raina MacIntyre, Sara Cajander, Ole Frobert
Original research: Invasive versus medically managed acute coronary syndromes with prior bypass (CABG-ACS): insights into the registry versus randomised trial populations (26 February, 2021)
Matthew M Y Lee, Mark C Petrie, Paul Rocchiccioli, Joanne Simpson, Colette E Jackson, David S Corcoran, Kenneth Mangion, Ammani Brown, Pio Cialdella, Novalia P Sidik, Margaret B McEntegart, Aadil Shaukat, Alan P Rae, Stuart H M Hood, Eileen E Peat, Iain N Findlay, Clare L Murphy, Alistair J Cormack, Nikolay B Bukov, Kanarath P Balachandran, Ian Ford, Olivia Wu, Alex McConnachie, Sarah J E Barry, Colin Berry
Original research: Downstream testing after CT coronary angiography: time for a rethink? (23 February, 2021)
Gareth Morgan-Hughes, Michelle Claire Williams, Margaret Loudon, Carl A Roobottom, Alice Veitch, Robin Van Lingen, Ben Holloway, Nicholas Bellenger, Matthias Schmitt, Russel Bull
Original research: Prognostic significance of BMI after PCI treatment in ST-elevation myocardial infarction: a cohort study from the Swedish Coronary Angiography and Angioplasty Registry (15 February, 2021)
Shabbar Jamaly, Bjorn Redfors, Elmir Omerovic, Lena Carlsson, Kristjan Karason
Original research: Coronary artery aneurysms: outcomes following medical, percutaneous interventional and surgical management (10 February, 2021)
Shameer Khubber, Rajdeep Chana, Chandramohan Meenakshisundaram, Kamal Dhaliwal, Mohomed Gad, Manpreet Kaur, Kinjal Banerjee, Beni Rai Verma, Shashank Shekhar, Muhummad Zia Khan, Muhammad Shahzeb Khan, Safi Khan, Yasser Sammour, Rayji Tsutsui, Rishi Puri, Ankur Kalra, Faisal G Bakaeen, Conrad Simpfendorfer, Stephen Ellis, Douglas Johnston, Gosta Pettersson, Samir Kapadia
Original research: Health-related quality of life 1–3 years post-myocardial infarction: its impact on prognosis (9 February, 2021)
Stuart Pocock, David B Brieger, Ruth Owen, Jiyan Chen, Mauricio G Cohen, Shaun Goodman, Christopher B Granger, José C Nicolau, Tabassome Simon, Dirk Westermann, Satoshi Yasuda, Katarina Hedman, Carl Mellström, Karolina Andersson Sundell, Richard Grieve
Original research: Estimating the extent of myocardial damage in patients with STEMI using the DETERMINE score (5 February, 2021)
Christina Tiller, Magdalena Holzknecht, Martin Reindl, Ivan Lechner, Verena Kalles, Felix Troger, Johannes Schwaiger, Agnes Mayr, Gert Klug, Christoph Brenner, Axel Bauer, Bernhard Metzler, Sebastian Johannes Reinstadler
Original research: COVID-19 pandemic is associated with mechanical complications in patients with ST-elevation myocardial infarction (5 February, 2021)
Satoshi Kitahara, Masashi Fujino, Satoshi Honda, Yasuhide Asaumi, Yu Kataoka, Fumiyuki Otsuka, Michio Nakanishi, Yoshio Tahara, Soshiro Ogata, Daisuke Onozuka, Kunihiro Nishimura, Tomoyuki Fujita, Kenichi Tsujita, Hisao Ogawa, Teruo Noguchi
Original research: Functional assessment of myocardial ischaemia by intracoronary ECG (18 January, 2021)
Marius Reto Bigler, Michael Stoller, Fabien Praz, George C M Siontis, Raphael Grossenbacher, Christine Tschannen, Christian Seiler
Original research: 180-day readmission risk model for older adults with acute myocardial infarction: the SILVER-AMI study (15 January, 2021)
John A Dodson, Alexandra M Hajduk, Terrence E Murphy, Mary Geda, Harlan M Krumholz, Sui Tsang, Michael G Nanna, Mary E Tinetti, Gregory Ouellet, Deborah Sybrant, Thomas M Gill, Sarwat I Chaudhry
Original research: Characteristics and outcomes of young patients with ST segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: retrospective analysis in a multiethnic Asian population (13 January, 2021)
Benjamin WL Tung, Zhe Yan Ng, William Kristanto, Kalyar Win Saw, Siew-Pang Chan, Winnie Sia, Koo Hui Chan, Mark Chan, William Kong, Ronald Lee, Joshua P Loh, Adrian F Low, Kian Keong Poh, Edgar Tay, Huay Cheem Tan, Tiong-Cheng Yeo, Poay Huan Loh

Congenital heart disease

Original research: Anomalous coronary artery origin from the opposite sinus in patients with bicuspid aortic valve: comparison with tricuspid aortic valve (21 June, 2021)
Saarwaani Vallabhajosyula, Margaret Fuchs, Li-Tan Yang, Jose Medina Inojosa, Tanya H Tajouri, Maurice Enriquez-Sarano, Sabrina D Phillips, Rajiv Gulati, Kyle W Klarich, Hector Michelena
Original research: Exercise prescription improves exercise tolerance in young children with CHD: a randomised clinical trial (14 May, 2021)
Sinead Callaghan, Margaret Louise Morrison, Pascal P McKeown, Christopher Tennyson, Andrew J Sands, Brian McCrossan, Brian Grant, Brian G Craig, Frank A Casey
Original research: Cross-sectional assessment of haemostatic profile and hepatic dysfunction in Fontan patients (10 May, 2021)
Joelle Julius Nicolaas Daems, Chantal Attard, Suelyn Van Den Helm, Johannes Breur, Yves D'Udekem, Karin du Plessis, Thomas G Wilson, David Winlaw, Thomas L Gentles, Paul Monagle, Vera Ignjatovic
Original research: Risk stratification of adults with congenital heart disease during the COVID-19 pandemic: insights from a multinational survey among European experts (21 April, 2021)
Francisco Javier Ruperti-Repilado, Daniel Tobler, Matthias Greutmann, Judith Bouchardy, Magalie Ladouceur, Laura Dos-Subira, Pastora Gallego, Harald Gabriel, Berto Bouma, Markus Schwerzmann
Original research: Patient information portal for congenital aortic and pulmonary valve disease: a stepped-wedge cluster randomised trial (23 March, 2021)
Jonathan R G Etnel, Lidia R Bons, Frederiek De Heer, Daniëlle Robbers-Visser, Ingrid M Van Beynum, Bart Straver, Monique RM Jongbloed, Philippine Kiès, Martijn G Slieker, Arie P J Van Dijk, Jolanda Kluin, Robin A Bertels, Elisabeth M W J Utens, Regina The, Eugene Van Galen, Barbara J M Mulder, Nico A Blom, Mark G Hazekamp, Jolien W Roos-Hesselink, Willem A Helbing, Ad J J C Bogers, Johanna J M Takkenberg
Original research: Dobutamine stress testing for the evaluation of atrial and diastolic ventricular function in Fontan patients (12 March, 2021)
Jelle P G van der Ven, Sjoerd S M Bossers, Eva van den Bosch, Niels Dam, Irene M Kuipers, Gabrielle G van Iperen, Lucia J M Kroft, Livia Kapusta, Arend D J ten Harkel, Willem A Helbing
Original research: Case of placental insufficiency and premature delivery in a Fontan pregnancy: physiological insights and considerations on risk stratification (19 February, 2021)
Maria Victoria Ordoñez, Giovanni Biglino, Massimo Caputo, Brenda Kelly, Aarthi Mohan, Johanna Trinder, Stephanie L Curtis
Original research: Echocardiographic screening for the anomalous aortic origin of coronary arteries (11 January, 2021)
Francesco Bianco, Massimo Colaneri, Valentina Bucciarelli, Francesca Chiara Surace, Federica Valentina Iezzi, Martina Primavera, Annaclara Biasi, Giuliano Giusti, Emanuela Berton, Monica Baldoni, Giulia Renda, Alessandra Baldinelli, Sabina Gallina, Marco Pozzi
Original research: Impact of pregnancy and risk factors for ventricular arrhythmias in women with tetralogy of Fallot (7 January, 2021)
Alessia Quattrone, Oyvind H Lie, Eirik Nestaas, Charlotte de Lange, Kirsti Try, Harald L Lindberg, Helge Skulstad, Gunnar Erikssen, Thor Edvardsen, Kristina Haugaa, Mette E Estensen

Health care delivery, economics and global health care

Original research: Sex-based inequalities in contemporary UK hospital management of stable chest pain (2 June, 2021)
Gareth Morgan-Hughes, Michelle Claire Williams, Margaret Loudon, Carl A Roobottom, Stelios Iacovides, Franchesca Wotton, Alice Veitch, Russel Bull
Original research: Access to MRI for patients with cardiac pacemakers and implantable cardioverter defibrillators (24 May, 2021)
Christopher Pieri, Anish Bhuva, Russell Moralee, Aderonke Abiodun, Deepa Gopalan, Giles H Roditi, James C Moon, Charlotte Manisty
Original research: CT coronary angiography and COVID-19: inpatient use in acute chest pain service (17 March, 2021)
Michael Cronin, Peter Wheen, Richard Armstrong, Rajesh Kumar, Alannah McMahon, Max White, Niall Sheehy, Geraldine McMahon, Ross T Murphy, Caroline Daly
Original research: Physical Activity after Cardiac EventS (PACES): a group education programme with subsequent text message support designed to increase physical activity in individuals with diagnosed coronary heart disease: a randomised controlled trial (26 February, 2021)
Louisa Y Herring, Helen Dallosso, Sally Schreder, Emily J Smith, Ghazala Waheed, Laura J Gray, Kamlesh Khunti, Thomas Yates, Patrick J Highton, Alex V Rowlands, Ian Hudson, Samuel Seidu, Melanie J Davies
Original research: Prospective multicentre cohort study of transthoracic echocardiography provision in the South West of the UK during the first wave of SARS-CoV-2 pandemic (27 January, 2021)
Rebecca Lucy Crook, Howell Williams, Mary Green, Stewart Brown, Richard Morris, Hannah Fletcher, Sarah Walters, Catherine Walsh, Anna Price, Samantha King, Christopher James McAloon
Original research: Sex disparities in the presentation, management and outcomes of patients with acute coronary syndrome: insights from the ACS QUIK trial (27 January, 2021)
Haitham Khraishah, Barrak Alahmad, Abdulhamied Alfaddagh, Sun Young Jeong, Njambi Mathenge, Mohamad Bassam Kassab, Dhaval Kolte, Erin D Michos, Mazen Albaghdadi

Heart failure and cardiomyopathies

Original research: Vascular comorbidities worsen prognosis of patients with heart failure hospitalised with COVID-19 (14 June, 2021)
Jacob Mok, Juan Carlos Malpartida, Kimberly O'Dell, Joshua Davis, Cuilan Gao, Harish Manyam
Original research: Efficacy of interventions to increase physical activity for people with heart failure: a meta-analysis (9 June, 2021)
Aliya Amirova, Theodora Fteropoulli, Paul Williams, Mark Haddad
Original research: Lockdown, slow down: impact of the COVID-19 pandemic on physical activity—an observational study (4 June, 2021)
Joanne Kathryn Taylor, Haarith Ndiaye, Matthew Daniels, Fozia Ahmed
Original research: Frailty and incident heart failure in older men: the British Regional Heart Study (4 June, 2021)
Douglas GJ McKechnie, A Olia Papacosta, Lucy T Lennon, Sheena E Ramsay, Peter H Whincup, S Goya Wannamethee
Original research: Improvements of predictive power of B-type natriuretic peptide on admission by mathematically estimating its discharge levels in hospitalised patients with acute heart failure (17 May, 2021)
Eiji Anegawa, Hiroyuki Takahama, Kunihiro Nishimura, Daisuke Onozuka, Yuki Irie, Kenji Moriuchi, Masashi Amano, Atsushi Okada, Makoto Amaki, Hideaki Kanzaki, Teruo Noguchi, Kengo Kusano, Satoshi Yasuda, Chisato Izumi
Original research: Five-year outcomes following left ventricular assist device implantation in England (11 May, 2021)
Alex Bottle, Puji Faitna, Paul P Aylin, Martin R Cowie
Determinants of LV dP/dt_max and QRS duration with different fusion strategies in cardiac resynchronisation therapy
(7 May, 2021)
Hans Henrik Odland, Torbjørn Holm, Lars Ove Gammelsrud, Richard Cornelussen, Erik Kongsgaard
Timing of pacemaker and ICD implantation in LMNA mutation carriers
(23 April, 2021)
Laura Helena Ollila, Kjell Nikus, Hannu Parikka, Sini Weckström, Heliö Tiina
Review: Update in imaging of cancer therapy-related cardiac toxicity in adults (16 April, 2021)
Esmée C de Baat, Willeke R Naaktgeboren, Tim Leiner, Arco J Teske, Jesse Habets, Heynric B Grotenhuis
Review: Current state of cardiac troponin testing in Duchenne muscular dystrophy cardiomyopathy: review and recommendations from the Parent Project Muscular Dystrophy expert panel (24 March, 2021)
Christopher F Spurney, Deborah Ascheim, Lawrence Charnas, Linda Cripe, Kan Hor, Nicholas King, Kathi Kinnett, Elizabeth M McNally, John-Michael Sauer, Lee Sweeney, Chet Villa, Larry W Markham
Original research: Incremental role of CT coronary angiography in the assessment of left ventricular diastolic function (19 March, 2021)
Aleksandra Lange, Harry Huntress, Jesse Steindl, Przemyslaw Palka
Original research: Association of early versus delayed normalisation of left ventricular ejection fraction with mortality in ischemic cardiomyopathy (15 March, 2021)
Walter B Schiffer, Andrew Perry, Elena Deych, David L Brown, Luigi Adamo
Original research: Sarcomere mutation negative hypertrophic cardiomyopathy is associated with ageing and obesity (26 February, 2021)
Alejandro E de Feria, Andrew E Kott, Jason R Becker
Original research: Associations between left bundle branch block with different PR intervals, QRS durations, heart rates and the risk of heart failure: a register-based cohort study using ECG data from the primary care setting (11 February, 2021)
Marc Meller Søndergaard, Johannes Riis, Karoline Willum Bodker, Steen Møller Hansen, Jesper Nielsen, Claus Graff, Adrian Holger Pietersen, Jonas Bille Nielsen, Bhupendar Tayal, Christoffer Polcwiartek, Christian Torp-Pedersen, Peter Soegaard, Kristian Hay Kragholm
Original research: Prognostic value of left ventricular mitral annular longitudinal displacement obtained by tissue Doppler imaging in patients with heart failure with reduced ejection fraction (25 January, 2021)
Morten Sengeløv, Peter Godsk Jørgensen, Niels Eske Bruun, Flemming Javier Olsen, Thomas Fritz-Hansen, Tor Biering-Sørensen
Original research: Tip of the iceberg: a tertiary care centre retrospective study of left ventricular hypertrophy aetiologies (13 January, 2021)
Maxime Beneyto, Eve Cariou, Jérémy Brunel, Alex Scripcariu, Hubert Delasnerie, Stéphanie Brun, Yoan Lavie-Badie, Delphine Dupin Deguine, Michel Galinier, Didier Carrié, Olivier Lairez
Original research: Characterisation of the patients with suspected heart failure: experience from the SHEAF registry (11 January, 2021)
Pankaj Garg, Ahmed Dakshi, Hosamadin Assadi, Andrew J Swift, Umna Naveed, Graham Fent, Nigel Lewis, Dominic Rogers, Athanasios Charalampopoulos, Abdallah Al-Mohammad

Interventional cardiology

Original research: Impact of emergency medical service delays on time to reperfusion and mortality in STEMI (7 May, 2021)
Ahmad Alrawashdeh, Ziad Nehme, Brett Williams, Karen Smith, Angela Brennan, Diem T Dinh, Danny Liew, Jeffrey Lefkovits, Dion Stub
Original research: Evaluation of latest viscoelastic coagulation assays in the transcatheter aortic valve implantation setting (20 April, 2021)
Jonathon Fanning, Shaun Roberts, Megan Merza, Chris Anstey, Karl Poon, Alexander Incani, Sarvesh Natani, John Fraser
Original research: Reintroduction of elective cardiac interventions in the era of COVID-19: the Barts experience (20 April, 2021)
Stephen Hamshere, Katrina Comer, Fizzah Choudhry, Krishna Rathod, Gordon Mills, Gordon Ferguson, Jonathan Lambourne, Majid Akhtar, Andrew Wragg, Mick Ozkor, Oliver Guttmann, Michael Mullen, Andreas Baumbach, Elliot Smith, Anthony Mathur, Dan Jones
Original research: Contemporary use of excimer laser in percutaneous coronary intervention with indications, procedural characteristics, complications and outcomes in a university teaching hospital (16 April, 2021)
Muhammad Jawad-Ul-Qamar, Harish Sharma, Vincenzo Vetrugno, Kully Sandhu, Peter F Ludman, Sagar N Doshi, Jonathan N Townend, Mohammed Osheiba, Alex Zaphiriou, Sohail Q Khan
Original research: Impact of ultrasound contrast agent during transoesophageal echocardiography on the sizing of the left atrial appendage (23 March, 2021)
Henning Ebelt, Sarah Goetze, Anja Weida, Alexandra Offhaus

Meta-analysis

Original research: Comparative safety of percutaneous ventricular assist device and intra-aortic balloon pump in acute myocardial infarction-induced cardiogenic shock (14 June, 2021)
Waqas Ullah, Mohamed Zghouzi, Maryam Mukhtar, Ali Banisad, Gaith Alhatemi, Yasar Sattar, Salman Zahid, Homam Moussa Pacha, Delair Gardi, M Chadi Alraies
Original research: Global effect of COVID-19 pandemic on the rate of acute coronary syndrome admissions: a comprehensive review of published literature (2 June, 2021)
Ayman Helal, Lamis Shahin, Mahmoud Abdelsalam, Mokhtar Ibrahim

Special populations

Review: Role of combining anticoagulant and antiplatelet agents in COVID-19 treatment: a rapid review (7 June, 2021)
Kamal Matli, Raymond Farah, Mario Maalouf, Nibal Chamoun, Christy Costanian, Georges Ghanem
Original research: Heavy alcohol drinking and subclinical echocardiographic abnormalities of structure and function (2 June, 2021)
Olena Iakunchykova, Henrik Schirmer, Darryl Leong, Sofia Malyutina, Andrew Ryabikov, Maria Averina, Alexander Kudryavtsev, Mikhail Kornev, Ekaterina Voronina, Andrey Paramonov, Tom Wilsgaard, David Leon
Original research: Risk of cardiac manifestations in adult mitochondrial disease caused by nuclear genetic defects (1 April, 2021)
Albert Zishen Lim, Daniel M Jones, Matthew G D Bates, Andrew M Schaefer, John O'Sullivan, Catherine Feeney, Maria E Farrugia, John P Bourke, Doug M Turnbull, Gráinne S Gorman, Robert McFarland, Yi Shiau Ng
Original research: Cardiac reserve by 6-minute walk stress echocardiography in systemic sclerosis (19 February, 2021)
Miharu Arase, Kenya Kusunose, Sae Morita, Natsumi Yamaguchi, Yukina Hirata, Susumu Nishio, Yuichiro Okushi, Takayuki Ise, Takeshi Tobiume, Koji Yamaguchi, Daiju Fukuda, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Masataka Sata

Valvular heart disease

Original research: Discordant severity criteria in patients with moderate aortic stenosis: prognostic implications (22 June, 2021)
Stephan M Pio, Mohammed R Amanullah, Steele C Butcher, Kenny Y Sin, Nina Ajmone Marsan, Philippe Pibarot, Nicolas M Van Mieghem, Zee Pin Ding, Philippe Généreux, Martin B Leon, See Hooi Ewe, Victoria Delgado, Jeroen J Bax
Original research: Coagulation derangement and risk factors for valve thrombosis following transcatheter aortic valve implantation (14 June, 2021)
Tiffany Patterson, Harriet Hurrell, Jack Lee, Giulia Esposito, Utkarsh Dutta, Julia Grapsa, Nicholas Aroney, Fiyyaz Ahmed-Jushuf, Christopher Allen, Ronak Rajani, Rebecca Preston, Christopher Young, Gianluca Lucchese, Kiran Parmar, Beverley Hunt, Bernard D Prendergast, Simon R Redwood
Original research: Gradient changes in bioprosthetic valve thrombosis: duration of anticoagulation and strategies to improve detection (24 May, 2021)
Jwan A Naser, Ioana Petrescu, Filip Ionescu, Vuyisile T Nkomo, Cristina Pislaru, Hartzell V Schaff, Patricia A Pellikka, Heidi M Connolly, Alexander C Egbe, Sorin V Pislaru
Original research: Community-based aortic stenosis detection: clinical and echocardiographic screening during influenza vaccination (21 May, 2021)
Richard Paul Steeds, Andrew Potter, Navjeet Mangat, Maren Fröhlich, Cornelia Deutsch, Peter Bramlage, Martin Thoenes
Review: Transcatheter mitral valve repair: an overview of current and future devices (28 April, 2021)
Ole De Backer, Ivan Wong, Maurizio Taramasso, Francesco Maisano, Olaf Franzen, Lars Søndergaard
Original research: Physiological and prognostic differences between types of exercise stress echocardiography for functional mitral regurgitation (22 April, 2021)
Nobuyuki Kagiyama, Misako Toki, Takuya Yuri, Shingo Aritaka, Akihiro Hayashida, Partho P Sengupta, Kiyoshi Yoshida
Original research: Mid-term outcome of children with latent rheumatic heart disease in eastern Nepal (5 April, 2021)
Nikesh Raj Shrestha, Dorothea Bruelisauer, Surendra Uranw, Rajan Mahato, Kunjang Sherpa, Krishna Agrawal, Martina Rothenbühler, Prahlad Karki, Thomas Pilgrim
Original research: Incidence and predictors of prosthesis–patient mismatch after TAVI using SAPIEN 3 in Asian: differences between the newer and older balloon-expandable valve (18 March, 2021)
Masaki Miyasaka, Norio Tada, Masataka Taguri, Shigeaki Kato, Yusuke Enta, Masaki Hata, Yusuke Watanabe, Toru Naganuma, Masahiro Yamawaki, Futoshi Yamanaka, Shinichi Shirai, Hiroshi Ueno, Kazuki Mizutani, Minoru Tabata, Kensuke Takagi, Masanori Yamamoto, Kentaro Hayashida
Original research: Prognostic comparison of atrial and ventricular functional mitral regurgitation (15 February, 2021)
Chisato Okamoto, Atsushi Okada, Kunihiro Nishimura, Kenji Moriuchi, Masashi Amano, Hiroyuki Takahama, Makoto Amaki, Takuya Hasegawa, Hideaki Kanzaki, Tomoyuki Fujita, Junjiro Kobayashi, Satoshi Yasuda, Chisato Izumi
Original research: First-phase ejection fraction: association with remodelling and outcome in aortic valve stenosis (11 February, 2021)
Rasmus Carter-Storch, Nils Sofus Borg Mogensen, Nicolaj Lyhne Christensen, Mulham Ali, Kristian Bach Laursen, Patricia A Pellikka, Jacob Eifer Moller, Jordi S Dahl
Original research: Natural course of tricuspid regurgitation and prognostic implications (9 February, 2021)
Marwin Bannehr, Christoph Roland Edlinger, Ulrike Kahn, Josephin Liebchen, Maki Okamoto, Valentin Hähnel, Victoria Dworok, Fabian Schipmann, Tanja Kücken, Karin Bramlage, Peter Bramlage, Anja Haase-Fielitz, Christian Butter
Original research: Predicting clinical outcome by indexed mitral valve tenting in functional mitral valve regurgitation (24 January, 2021)
Maria von Stumm, Florian Dudde, Theresa Holst, Tatjana Sequeira-Gross, Jonas Pausch, Lisa Müller, Christoph R Sinning, Hermann Reichenspurner, E Girdauskas
Review: Minimally invasive surgery versus transcatheter aortic valve replacement: a systematic review and meta-analysis (17 January, 2021)
Ahmed Sayed, Salma Almotawally, Karim Wilson, Malak Munir, Ahmed Bendary, Ahmed Ramzy, Sameer Hirji, Abdelrahman Ibrahim Abushouk
Original research: Management of patients with severe aortic stenosis in the TAVI-era: how recent recommendations are translated into clinical practice (11 January, 2021)
Alexander Lauten, Tanja K Rudolph, David Messika-Zeitoun, Jeetendra Thambyrajah, Antonio Serra, Eberhard Schulz, Norbert Frey, Jiri Maly, Marco Aiello, Guy Lloyd, Alessandro Santo Bortone, Alberto Clerici, Georg Delle-Karth, Johannes Rieber, Ciro Indolfi, Massimo Mancone, Loic Belle, Martin Arnold, Berto J Bouma, Matthias Lutz, Cornelia Deutsch, Jana Kurucova, Martin Thoenes, Peter Bramlage, Richard Paul Steeds
Original research: Sex differences in patients undergoing transcatheter aortic valve replacement in Asia (8 January, 2021)
Paul T L Chiam, Kentaro Hayashida, Yusuke Watanabe, Wei-Hsian Yin, Hsien-Li Kao, Michael K Y Lee, Fabio Enrique Posas, Mann Chandavimol, Wacin Buddhari, Timothy C Dy, Ngoc Quang Nguyen, Won Jang Kim, Kiyuk Chang, Mao-Shin Lin, Yat-Yin Lam, Hung Manh Pham, Shaiful Azmi Yahaya, Kay Woon Ho, Wenzhi Pan, Xian-bao Liu, Jian'an Wang, Hyo Soo Kim, Mao Chen
Original research: IMPULSE: the impact of gender on the presentation and management of aortic stenosis across Europe (8 January, 2021)
Richard Paul Steeds, David Messika-Zeitoun, Jeetendra Thambyrajah, Antonio Serra, Eberhard Schulz, Jiri Maly, Marco Aiello, Tanja K Rudolph, Guy Lloyd, Alessandro Santo Bortone, Alberto Clerici, Georg Delle-Karth, Johannes Rieber, Ciro Indolfi, Massimo Mancone, Loic Belle, Alexander Lauten, Martin Arnold, Berto J Bouma, Matthias Lutz, Cornelia Deutsch, Jana Kurucova, Martin Thoenes, Peter Bramlage, Norbert Frey

Viewpoint

The imperative of consistency and proficiency in cardiac devices implant skills training (10 May, 2021)
Jorio Mascheroni, Lluís Mont, Martin Stockburger, Ashish Patwala, Hartwig Retzlaff, Anthony G Gallagher
Icosapent ethyl: scientific and legal controversies (22 April, 2021)
Gregory Curfman, Emile Shehada
‘Valve for Life’: tackling the deficit in transcatheter treatment of heart valve disease in the UK (25 March, 2021)
Noman Ali, Amir Faour, John Rawlins, Sam Dawkins, Clare E Appleby, Philip MacCarthy, Jonathan Byrne, Uday Trivedi, Nick Curzen, Adrian P Banning, Peter Ludman, Daniel J Blackman
Four pillars of heart failure: contemporary pharmacological therapy for heart failure with reduced ejection fraction (2 March, 2021)
Sam Straw, Melanie McGinlay, Klaus K Witte

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Current Issue

January 2021 - Volume 8 - 1

Editorial

Aortic and vascular disease

Arrhythmias and sudden death

Basic and translational research

Cardiac risk factors and prevention

Cardiac surgery

Coronary artery disease

Congenital heart disease

Health care delivery, economics and global health care

Heart failure and cardiomyopathies

Interventional cardiology

Meta-analysis

Special populations

Valvular heart disease

Viewpoint

Correction

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Current Issue

January 2021 - Volume 8 - 1

Editorial

Aortic and vascular disease

Arrhythmias and sudden death

Basic and translational research

Cardiac risk factors and prevention

Cardiac surgery

Coronary artery disease

Congenital heart disease

Health care delivery, economics and global health care

Heart failure and cardiomyopathies

Interventional cardiology

Meta-analysis

Special populations

Valvular heart disease

Viewpoint

Correction