Article Text

Download PDFPDF

Original research
Inconsistency in aortic stenosis severity between CT and echocardiography: prevalence and insights into mechanistic differences using computational fluid dynamics
  1. Tarun Kumar Mittal1,2,
  2. Luise Reichmuth1,
  3. Sanjeev Bhattacharyya1,
  4. Manish Jain1,
  5. Aigul Baltabaeva3,
  6. Shelley Rahman Haley1,
  7. Saeed Mirsadraee1,2,
  8. Vasileios Panoulas2,3,
  9. Tito Kabir3,
  10. Edward David Nicol1,2,
  11. Miles Dalby2,3 and
  12. Quan Long4
  1. 1 Heart Assessment, Royal Brompton and Harefield NHS Foundation Trust, London, Middlesex, UK
  2. 2 Faculty of Medicine, NHLI, Imperial College London, London, United Kingdom
  3. 3 Cardiology, Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom
  4. 4 Institute of Bioengineering, Brunel University, Uxbridge, Middlesex, UK
  1. Correspondence to Dr Tarun Kumar Mittal; t.mittal{at}outlook.com

Footnotes

  • Contributors TKM developed the hypothesis and design the study. LR, SB, MJ and TKM collected the clinical, echocardiographic and CT data. SM was involved in the study of interobserver variability. QL was responsible for the computational fluid dynamics. TM, SB, AB, SRH, VP, TK, EDN, MD and QL assisted in study drafts and final version.

  • Funding This research has received no specific grant from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests No, there are no competing interests for any author.

  • Patient consent for publication Not required.

  • Ethics approval NHS (National Health Service) research ethics approval was obtained (IRAS Project ID: 2014HS002H).

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data availability statement Data are available on reasonable request.

View Full Text

Statistics from Altmetric.com

Footnotes

  • Contributors TKM developed the hypothesis and design the study. LR, SB, MJ and TKM collected the clinical, echocardiographic and CT data. SM was involved in the study of interobserver variability. QL was responsible for the computational fluid dynamics. TM, SB, AB, SRH, VP, TK, EDN, MD and QL assisted in study drafts and final version.

  • Funding This research has received no specific grant from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests No, there are no competing interests for any author.

  • Patient consent for publication Not required.

  • Ethics approval NHS (National Health Service) research ethics approval was obtained (IRAS Project ID: 2014HS002H).

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data availability statement Data are available on reasonable request.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.