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Heart failure: a story of damage, fatigue and injury?
  1. Prithwish Banerjee1,2,3
  1. 1Department of Cardiology, University Hospitals Coventry and Warwickshire, Coventry, UK
  2. 2Faculty of Health and Life Sciences, Coventry University, Coventry, UK
  3. 3Warwick Medical School, University of Warwick, Coventry, UK
  1. Correspondence to Prof Prithwish Banerjee; Prithwish.Banerjee{at}


Heart failure has been recognised for years but the complete picture has been difficult to clearly understand. This article aims to try and put forward a proposed mechanistic explanation to encompass all that we see within the clinical heart failure syndrome using supporting published evidence. The aim of the article is to link, using published evidence, all the known varieties of heart failure into a spectrum that is explained by simple interlinked processes. In addition, the concept of routinely looking for reversibility of left ventricular dysfunction is introduced.

  • heart failure
  • hfpef
  • hfref
  • damage
  • fatigue

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  • Contributors The entire article is conceived and written by PB alone.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement No additional data available.

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