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Coronary artery disease is associated with persistent lower quality of life in women
  1. Baris Gencer1 and
  2. François Girardin2,3
  1. 1Cardiology Division, University Hospital of Geneva, Geneva, Switzerland
  2. 2Medical Directorate, University Hospital of Geneva, Geneva, Switzerland
  3. 3Department of Anesthesiology, Intensive Care and Clinical Pharmacology and Toxicology, University Hospitals and University of Geneva, Faculty of Medicine, Geneva, Switzerland
  1. Correspondence to Dr Baris Gencer; Baris.Gencer{at}

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Gijsberts et al reported the unfavourable impact of coronary artery disease (CAD) on the health-reported quality of life (HRQoL) in women using data from the Utrecht Coronary Biobank cohort. (Add Ref openhrt-2014-0000231.R2) The mean self-rated health status based on the EuroQol-5D (EQ-5D) was significantly lower in women compared with men (6.46±1.40 vs 6.84±1.49, p<0.001). In all the domains of the RAND-36, women reported poorer outcomes than men, especially for physical and social functions. In addition, compared to the general Dutch population, women with CAD had significantly poorer HRQoL compared with men. This study adds relevant clinical implications of the secondary prevention of CAD in patients within a large sample (1020 men and 401 women with CAD) and gives an accurate description of the impaired domains of the HRQoL in patients with CAD. The persisting poorer outcomes of HRQoL in women suggest that gender-related factor remains a major issue regardless of the disease severity and treatment.

Recently, data from among patients who had premature acute coronary syndromes (ACS) taken from the GENESIS-PRAXY study (GENdEr and Sex …

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