Sympathetic autonomic dysfunction and impaired cardiovascular performance in higher risk surgical patients: implications for perioperative sympatholysis

John Whittle; Alexander Nelson; James M Otto; Robert C M Stephens; Daniel S Martin; J Robert Sneyd; Richard Struthers; Gary Minto; Gareth L Ackland

doi:10.1136/openhrt-2015-000268

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Sympathetic autonomic dysfunction and impaired cardiovascular performance in higher risk surgical patients: implications for perioperative sympatholysis

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John Whittle Division of Medicine, Department of Clinical Physiology, University College London, London, UK PubMed articles Google scholar articles
Alexander Nelson UCL Medical School, University College London, London, UK PubMed articles Google scholar articles
James M Otto Division of Surgery and Interventional Science, University College London, Royal Free Hospital, London, UK PubMed articles Google scholar articles
Robert C M Stephens Department of Anaesthesia, University College London Hospitals NHS Trust, London, UK PubMed articles Google scholar articles
Daniel S Martin Division of Surgery and Interventional Science, University College London, Royal Free Hospital, London, UK PubMed articles Google scholar articles
J Robert Sneyd Plymouth University, Peninsula Schools of Medicine and Dentistry, Plymouth, London, UK PubMed articles Google scholar articles
Richard Struthers Plymouth University, Peninsula Schools of Medicine and Dentistry, Plymouth, London, UK PubMed articles Google scholar articles
Gary Minto Plymouth University, Peninsula Schools of Medicine and Dentistry, Plymouth, London, UK PubMed articles Google scholar articles
Gareth L Ackland Division of Medicine, Department of Clinical Physiology, University College London, London, UK Department of Neuroscience, Physiology and Pharmacology, Centre for Cardiovascular and Metabolic Neuroscience, University College London, London, UK William Harvey Research Institute, Queen Mary University of London, London, UK PubMed articles Google scholar articles

Correspondence to Dr Gareth L Ackland; g.ackland{at}ucl.ac.uk

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Citation

Whittle J, Nelson A, Otto JM, et al

Sympathetic autonomic dysfunction and impaired cardiovascular performance in higher risk surgical patients: implications for perioperative sympatholysis

Open Heart 2015;2:e000268. doi: 10.1136/openhrt-2015-000268

Publication history

Received March 17, 2015
Revision received June 8, 2015
Accepted June 18, 2015
First published October 19, 2015.

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April 30, 2020

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Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/

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