Aims In symptomatic patients with suspected coronary artery disease (CAD), computed
tomographic angiography (CTA) improves patient selection for invasive coronary …

Incubation of endothelial cells in vitro with high concentrations of glucose activates protein
kinase C (PKC) and increases nitric oxide synthase (NOS III) gene expression as well as …

The hemodynamic and anti-ischemic effects of nitroglycerin (NTG) are rapidly blunted as a
result of the development of nitrate tolerance. With initiation of NTG therapy, it is possible to …

Background: Coronary computed tomographic angiography (CTA) plus estimation of
fractional flow reserve using CTA (FFRCT) safely and effectively guides initial care over 90 …

Increased NAD (P) H oxidase-mediated superoxide production in renovascular
hypertension: Evidence for an involvement of protein kinase C. Background Angiotensin II …

Nebivolol is a β1-receptor antagonist with vasodilator and antioxidant properties. Because
the vascular NADPH oxidase is an important superoxide source, we studied the effect of …

Background: Fractional flow reserve estimated using computed tomography (FFRCT) might
improve evaluation of patients with chest pain. Objectives: The authors sought to determine …

Hyperglycemia is the major causal factor in the development of endothelial dysfunction in
patients with diabetes mellitus. Although the mechanisms underlying this phenomenon are …

Long-term nitroglycerin (NTG) treatment has been shown to be associated with cross-
tolerance to endothelium-dependent vasodilators. It may involve increased production of …

Aims The influence of age on baseline demographics and outcomes of patients selected for
MitraClip has not been previously investigated. Methods and results Baseline demographics …