Ablation index, a novel marker of ablation lesion quality: prediction of pulmonary vein reconnection at repeat electrophysiology study and regional differences in target …

M Das, JJ Loveday, GJ Wynn, S Gomes, Y Saeed… - Europace, 2017 - academic.oup.com
Aims Force–Time Integral (FTI) is commonly used as a marker of ablation lesion quality
during pulmonary vein isolation (PVI), but does not incorporate power. Ablation Index (AI) is …

Use of ablation index-guided ablation results in high rates of durable pulmonary vein isolation and freedom from arrhythmia in persistent atrial fibrillation patients: the …

A Hussein, M Das, S Riva, M Morgan… - Circulation …, 2018 - Am Heart Assoc
Background Catheter ablation for persistent atrial fibrillation (AF) is associated with less
favorable outcomes than for paroxysmal AF. Substrate modification is often added to …

Prospective use of Ablation Index targets improves clinical outcomes following ablation for atrial fibrillation

A Hussein, M Das, V Chaturvedi… - Journal of …, 2017 - Wiley Online Library
Aims Late recovery of ablated tissue leading to reconnection of pulmonary veins remains
common following radiofrequency catheter ablation for AF. Ablation Index (AI), a novel …

Recurrence of atrial tachyarrhythmia during the second month of the blanking period is associated with more extensive pulmonary vein reconnection at repeat …

M Das, GJ Wynn, M Morgan, B Lodge… - Circulation …, 2015 - Am Heart Assoc
Background—Current guidelines recommend a 3-month blanking period after pulmonary
vein isolation (PVI) as early recurrence of atrial tachyarrhythmia (ERAT) may be due to …

Local impedance for the optimization of radiofrequency lesion delivery: a review of bench and clinical data

GS Chu, P Calvert, P Futyma, WY Ding… - Journal of …, 2022 - Wiley Online Library
Introduction Radiofrequency catheter ablation is a cornerstone of treatment for many cardiac
arrhythmias. Progression in three‐dimensional mapping and contact‐force sensing …

Pulmonary vein re-isolation as a routine strategy regardless of symptoms: the PRESSURE randomized controlled trial

M Das, GJ Wynn, Y Saeed, S Gomes, M Morgan… - JACC: Clinical …, 2017 - jacc.org
Objectives: The goal of this study was to determine whether a strategy of early re-isolation of
pulmonary vein (PV) reconnection in all patients, regardless of symptoms, would reduce the …

Fundamental differences in electrophysiologic and electroanatomic substrate between ischemic cardiomyopathy patients with and without clinical ventricular …

HM Haqqani, JM Kalman, KC Roberts-Thomson… - Journal of the American …, 2009 - jacc.org
Objectives: The aim of this study was to compare the electrophysiologic substrate in
ischemic cardiomyopathy (ICM) patients with and without sustained monomorphic …

Same‐day discharge in selected patients undergoing atrial fibrillation ablation

S Bartoletti, M Mann, A Gupta, AM Khan… - Pacing and Clinical …, 2019 - Wiley Online Library
Background Atrial fibrillation (AF) ablation is a complex procedure, generally requiring at
least one overnight hospital stay. We investigated the safety and feasibility of early …

Systematic re‐evaluation of SCN5A variants associated with Brugada syndrome

NC Denham, CM Pearman, WY Ding… - Journal of …, 2019 - Wiley Online Library
Background A large number of SCN5A variants have been reported to underlie Brugada
syndrome (BrS). However, the evidence supporting individual variants is highly …

Biatrial linear ablation in sustained nonpermanent AF: results of the substrate modification with ablation and antiarrhythmic drugs in nonpermanent atrial fibrillation …

GJ Wynn, S Panikker, M Morgan, M Hall, J Waktare… - Heart Rhythm, 2016 - Elsevier
Background More advanced atrial fibrillation (AF) is associated with lower success rates
after pulmonary vein isolation (PVI), and the optimal ablation strategy is uncertain …