Efficacy of catheter ablation for persistent atrial fibrillation: a systematic review and meta-analysis of evidence from randomized and nonrandomized controlled trials

GJ Wynn, M Das, LJ Bonnett, S Panikker… - Circulation …, 2014 - Am Heart Assoc
Background—Catheter ablation (CA) is commonly performed for persistent atrial fibrillation,
but few high-quality randomized controlled trials (RCTs) exist, leading to funding restrictions …

Ablation index, a novel marker of ablation lesion quality: prediction of pulmonary vein reconnection at repeat electrophysiology study and regional differences in target …

M Das, JJ Loveday, GJ Wynn, S Gomes, Y Saeed… - Europace, 2017 - academic.oup.com
Aims Force–Time Integral (FTI) is commonly used as a marker of ablation lesion quality
during pulmonary vein isolation (PVI), but does not incorporate power. Ablation Index (AI) is …

Use of ablation index-guided ablation results in high rates of durable pulmonary vein isolation and freedom from arrhythmia in persistent atrial fibrillation patients: the …

A Hussein, M Das, S Riva, M Morgan… - Circulation …, 2018 - Am Heart Assoc
Background Catheter ablation for persistent atrial fibrillation (AF) is associated with less
favorable outcomes than for paroxysmal AF. Substrate modification is often added to …

Prospective use of Ablation Index targets improves clinical outcomes following ablation for atrial fibrillation

A Hussein, M Das, V Chaturvedi… - Journal of …, 2017 - Wiley Online Library
Aims Late recovery of ablated tissue leading to reconnection of pulmonary veins remains
common following radiofrequency catheter ablation for AF. Ablation Index (AI), a novel …

Decrement evoked potential mapping: basis of a mechanistic strategy for ventricular tachycardia ablation

N Jackson, S Gizurarson, K Viswanathan… - Circulation …, 2015 - Am Heart Assoc
Background—Substrate-based mapping for ventricular tachycardia (VT) ablation is
hampered by its inability to determine critical sites of the VT circuit. We hypothesized that …

Recurrence of atrial tachyarrhythmia during the second month of the blanking period is associated with more extensive pulmonary vein reconnection at repeat …

M Das, GJ Wynn, M Morgan, B Lodge… - Circulation …, 2015 - Am Heart Assoc
Background—Current guidelines recommend a 3-month blanking period after pulmonary
vein isolation (PVI) as early recurrence of atrial tachyarrhythmia (ERAT) may be due to …

Local catheter impedance drop during pulmonary vein isolation predicts acute conduction block in patients with paroxysmal atrial fibrillation: initial results of the …

M Das, A Luik, E Shepherd, M Sulkin, J Laughner… - EP …, 2021 - academic.oup.com
Aims Radiofrequency ablation creates irreversible cardiac damage through resistive heating
and this temperature change results in a generator impedance drop. Evaluation of a novel …

Pulmonary vein re-isolation as a routine strategy regardless of symptoms: the PRESSURE randomized controlled trial

M Das, GJ Wynn, Y Saeed, S Gomes, M Morgan… - JACC: Clinical …, 2017 - jacc.org
Objectives: The goal of this study was to determine whether a strategy of early re-isolation of
pulmonary vein (PV) reconnection in all patients, regardless of symptoms, would reduce the …

Relationship between contact force sensing technology and medium‐term outcome of atrial fibrillation ablation: a multicenter study of 600 patients

JWE Jarman, S Panikker, M Das… - Journal of …, 2015 - Wiley Online Library
Contact Force Sensing AF Ablation Outcomes Introduction Contact force sensing (CFS)
technology improves acute pulmonary vein isolation durability; however, its impact on the …

Long-term outcomes after ablation of persistent atrial fibrillation: an observational study over 6 years

GJ Wynn, M El-Kadri, I Haq, M Das, S Modi… - Open …, 2016 - openheart.bmj.com
Objectives To address the limited long-term outcome data for catheter ablation (CA) of
persistent atrial fibrillation (PeAF), we analysed consecutive ablations performed at our …