Cardiac innervation and sudden cardiac death

K Fukuda, H Kanazawa, Y Aizawa, JL Ardell… - Circulation …, 2015 - Am Heart Assoc
Afferent and efferent cardiac neurotransmission via the cardiac nerves intricately modulates
nearly all physiological functions of the heart (chronotropy, dromotropy, lusitropy, and …

Development, maturation, and transdifferentiation of cardiac sympathetic nerves

K Kimura, M Ieda, K Fukuda - Circulation research, 2012 - Am Heart Assoc
The heart is electrically and mechanically controlled as a syncytium by the autonomic
nervous system. The cardiac nervous system comprises the sympathetic, parasympathetic …

[HTML][HTML] Cardiomyocytes can be generated from marrow stromal cells in vitro

S Makino, K Fukuda, S Miyoshi… - The Journal of …, 1999 - Am Soc Clin Investig
We have isolated a cardiomyogenic cell line (CMG) from murine bone marrow stromal cells.
Stromal cells were immortalized, treated with 5-azacytidine, and spontaneously beating cells …

Molecular and cellular neurocardiology: development, and cellular and molecular adaptations to heart disease

BA Habecker, ME Anderson, SJ Birren… - The Journal of …, 2016 - Wiley Online Library
The nervous system and cardiovascular system develop in concert and are functionally
interconnected in both health and disease. This white paper focuses on the cellular and …

[PDF][PDF] Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes

S Tohyama, F Hattori, M Sano, T Hishiki, Y Nagahata… - Cell stem cell, 2013 - cell.com
Heart disease remains a major cause of death despite advances in medical technology.
Heart-regenerative therapy that uses pluripotent stem cells (PSCs) is a potentially promising …

Nonhematopoietic mesenchymal stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction

H Kawada, J Fujita, K Kinjo, Y Matsuzaki, M Tsuma… - Blood, 2004 - ashpublications.org
Bone marrow (BM) cells are reported to contribute to the process of regeneration following
myocardial infarction. However, the responsible BM cells have not been fully identified …

[PDF][PDF] Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells

T Seki, S Yuasa, M Oda, T Egashira, K Yae… - Cell stem cell, 2010 - cell.com
The direct reprogramming of somatic cells to produce induced pluripotent stem cells (iPSCs)
is a prominent recent advance in stem cell biology (Takahashi and Yamanaka, 2006) …

Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia–reperfusion injury

K Hayashida, M Sano, I Ohsawa, K Shinmura… - Biochemical and …, 2008 - Elsevier
Inhalation of hydrogen (H2) gas has been demonstrated to limit the infarct volume of brain
and liver by reducing ischemia–reperfusion injury in rodents. When translated into clinical …

Temporal dynamics of cardiac immune cell accumulation following acute myocardial infarction

X Yan, A Anzai, Y Katsumata, T Matsuhashi… - Journal of molecular and …, 2013 - Elsevier
Acute myocardial infarction (MI) causes sterile inflammation, which is characterized by
recruitment and activation of innate and adaptive immune system cells. Here we delineate …

Development of regenerative cardiomyocytes from mesenchymal stem cells for cardiovascular tissue engineering

K Fukuda - Artificial organs, 2001 - Wiley Online Library
We have isolated a cardiomyogenic (CMG) cell line from murine bone marrow stroma.
Stromal cells were immortalized, treated with 5‐azacytidine, and spontaneous beating cells …