[HTML][HTML] Origins and evolution of the Western diet: health implications for the 21st century1, 2

L Cordain, SB Eaton, A Sebastian, N Mann… - The American journal of …, 2005 - Elsevier
There is growing awareness that the profound changes in the environment (eg, in diet and
other lifestyle conditions) that began with the introduction of agriculture and animal …

Vitamin D deficiency: an important, common, and easily treatable cardiovascular risk factor?

JH Lee, JH O'Keefe, D Bell, DD Hensrud… - Journal of the American …, 2008 - jacc.org
Vitamin D deficiency is a highly prevalent condition, present in approximately 30% to 50% of
the general population. A growing body of data suggests that low 25-hydroxyvitamin D …

Optimal low-density lipoprotein is 50 to 70 mg/dl: lower is better and physiologically normal

JH O'Keefe, L Cordain, WH Harris, RM Moe… - Journal of the American …, 2004 - jacc.org
The normal low-density lipoprotein (LDL) cholesterol range is 50 to 70 mg/dl for native
hunter-gatherers, healthy human neonates, free-living primates, and other wild mammals …

A randomized, controlled trial of the effects of remote, intercessory prayer on outcomes in patients admitted to the coronary care unit

WS Harris, M Gowda, JW Kolb… - Archives of Internal …, 1999 - jamanetwork.com
Context Intercessory prayer (praying for others) has been a common response to sickness
for millennia, but it has received little scientific attention. The positive findings of a previous …

Exercise and the cardiovascular system: clinical science and cardiovascular outcomes

CJ Lavie, R Arena, DL Swift, NM Johannsen… - Circulation …, 2015 - Am Heart Assoc
Substantial evidence has established the value of high levels of physical activity, exercise
training (ET), and overall cardiorespiratory fitness in the prevention and treatment of …

Angiotensin-converting enzyme inhibitors or angiotensin receptor blockers for prevention of type 2 diabetes: a meta-analysis of randomized clinical trials

H Abuissa, PG Jones, SP Marso, JH O'Keefe - Journal of the American …, 2005 - jacc.org
Objectives: We sought to investigate the role of angiotensin-converting enzyme (ACE)
inhibitors and angiotensin receptor blockers (ARBs) in preventing the new onset of type 2 …

Postprandial hyperglycemia/hyperlipidemia (postprandial dysmetabolism) is a cardiovascular risk factor

JH O'Keefe, DSH Bell - The American journal of cardiology, 2007 - Elsevier
Epidemiologic data indicate that a postprandial state characterized by abnormally increased
levels of glucose and lipids (also referred to as postprandial dysmetabolism) is an …

Dietary strategies for improving post-prandial glucose, lipids, inflammation, and cardiovascular health

JH O'Keefe, NM Gheewala, JO O'Keefe - Journal of the American College …, 2008 - jacc.org
The highly processed, calorie-dense, nutrient-depleted diet favored in the current American
culture frequently leads to exaggerated supraphysiological post-prandial spikes in blood …

Autonomic tone as a cardiovascular risk factor: the dangers of chronic fight or flight

BM Curtis, JH O'Keefe Jr - Mayo Clinic Proceedings, 2002 - Elsevier
Chronic imbalance of the autonomic nervous system is a prevalent and potent risk factor for
adverse cardiovascular events, including mortality. Although not widely recognized by …

Potential adverse cardiovascular effects from excessive endurance exercise

JH O'Keefe, HR Patil, CJ Lavie, A Magalski… - Mayo Clinic …, 2012 - Elsevier
A routine of regular exercise is highly effective for prevention and treatment of many
common chronic diseases and improves cardiovascular (CV) health and longevity …