Clinical outcomes of fractional flow reserve by computed tomographic angiography-guided diagnostic strategies vs. usual care in patients with suspected coronary …

PS Douglas, G Pontone, MA Hlatky… - European heart …, 2015 - academic.oup.com
Aims In symptomatic patients with suspected coronary artery disease (CAD), computed
tomographic angiography (CTA) improves patient selection for invasive coronary …

1-Year Outcomes of FFRCT-Guided Care in Patients With Suspected Coronary Disease: The PLATFORM Study

PS Douglas, B De Bruyne, G Pontone, MR Patel… - Journal of the American …, 2016 - jacc.org
Background: Coronary computed tomographic angiography (CTA) plus estimation of
fractional flow reserve using CTA (FFRCT) safely and effectively guides initial care over 90 …

Quality-of-life and economic outcomes of assessing fractional flow reserve with computed tomography angiography: PLATFORM

MA Hlatky, B De Bruyne, G Pontone, MR Patel… - Journal of the American …, 2015 - jacc.org
Background: Fractional flow reserve estimated using computed tomography (FFRCT) might
improve evaluation of patients with chest pain. Objectives: The authors sought to determine …

Delayed environmental enrichment reverses sevoflurane-induced memory impairment in rats

J Shih, LDV May, HE Gonzalez, EW Lee… - The Journal of the …, 2012 - pubs.asahq.org
Background Anesthesia given to immature rodents causes cognitive decline, raising the
possibility that the same might be true for millions of children undergoing surgical …

Longitudinal analysis of the electroencephalogram and sleep phenotype in the R6/2 mouse model of Huntington's disease

SP Fisher, SW Black, MD Schwartz, AJ Wilk, TM Chen… - Brain, 2013 - academic.oup.com
Deficits in sleep and circadian organization have been identified as common early features
in patients with Huntington's disease that correlate with symptom severity and may be …

FFR derived from coronary CT angiography in nonculprit lesions of patients with recent STEMI

S Gaur, CA Taylor, JM Jensen, HE Bøtker… - JACC: Cardiovascular …, 2017 - jacc.org
Objectives: This study sought to determine the diagnostic performance of noninvasive
fractional flow reserve (FFR) derived from coronary computed tomography angiography …

[HTML][HTML] Effect of the ratio of coronary arterial lumen volume to left ventricle myocardial mass derived from coronary CT angiography on fractional flow reserve

CA Taylor, S Gaur, J Leipsic, S Achenbach… - Journal of …, 2017 - Elsevier
Background We hypothesize that in patients with suspected coronary artery disease (CAD),
lower values of the ratio of total epicardial coronary arterial lumen volume to left ventricular …

[HTML][HTML] The hypocretin/orexin antagonist almorexant promotes sleep without impairment of performance in rats

SR Morairty, AJ Wilk, WU Lincoln, TC Neylan… - Frontiers in …, 2014 - frontiersin.org
The hypocretin receptor (HcrtR) antagonist almorexant (ALM) has potent hypnotic actions
but little is known about neurocognitive performance in the presence of ALM. HcrtR …

An FFRCT diagnostic strategy versus usual care in patients with suspected coronary artery disease planned for invasive coronary angiography at German sites: one …

R Colleran, PS Douglas, M Hadamitzky… - Open …, 2017 - openheart.bmj.com
Aim Diagnostic evaluation practices for suspected coronary artery disease (CAD) may vary
between countries. Our objective was to compare a CT-derived fractional flow reserve …

Patient characteristics and healthcare resource utilization among patients with COPD new to LAMA/LABA fixed-dose combination treatment in US-based real-world …

B Ding, L Kallenbach, L Slipski, A Wilk… - … Journal of Chronic …, 2020 - Taylor & Francis
Introduction This retrospective, observational cohort study utilized an integrated dataset from
an electronic health records system and a claims database to describe demographic and …