Biological differences in paclitaxel- and sirolimus-coated balloons

ORIGINAL RESEARCH

Mar 29
Biological differences in paclitaxel- and sirolimus-coated balloons
Kazuki Aihara, Gaku Nakazawa, et al.
This preclinical study compared the drug effects and safety of low-dose paclitaxel, regular-dose paclitaxel and sirolimus-coated drug-coated balloons when inflated in rabbit iliac arteries. Paclitaxel-coated balloons showed higher efficacy and lower distal embolization risk than the sirolimus-coated balloon.

ORIGINAL RESEARCH

Mar 29
Redo-TAVI with ACURATE neo2 in SAPIEN 3
Davide Meier, Janarthanan Sathananthan, et al.
Bench testing assessed redo-TAVI using the ACURATE platform within a SAPIEN 3 vs a new SAPIEN 3 valve, finding the ACURATE resulted in better hydrodynamics, less pinwheeling, and a taller neoskirt.
Redo-TAVI with ACURATE neo2 in SAPIEN 3

ORIGINAL RESEARCH

Mar 28
Vascular closure algorithm for TF-TAVI
Liesbeth Rosseel, MD; Ole De Backer, MD, PhD; et al.
This observational study evaluated the MultiCLOSE vascular closure algorithm in 630 patients undergoing transfemoral TAVI across 3 hospitals. Complete haemostasis was achieved in 98%, with minor and major vascular complication rates of 2.2% and 0.6% respectively.
Vascular closure algorithm for TF-TAVI

EDITORIAL

Mar 28
Femoral access closure algorithm after TAVI
Thomas Pilgrim; Annette Maznyczka
The study assessed strategies to reduce vascular access site complications after TAVI, including ultrasound-guided puncture, closure devices, and pre-procedure imaging. Implementation of standardized protocols was associated with decreased rates of vascular complications over time.
Femoral access closure algorithm after TAVI
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Mar 18
Meet Cory, your new AI Assistant!

Since the launch of its new website in February, EuroIntervention has harnessed the power of AI, integrating this cutting-edge technology in the development and improvement of features such as an optimised user interface and a powerful search engine.

Now, EuroIntervention is unveiling its new AI assistant – the first of its kind in the field of academic publishing - designed to accompany readers and enhance their reading experience.

Meet Cory, your new AI Assistant!

DEBATE

Mar 18
Ischaemic and viability testing for guiding PCI are overrated: pros and cons
Margaret B. McEntegart; Victoria Delgado et al.
Two large randomized trials found no benefit of an invasive strategy guided by ischaemia and viability testing over medical therapy alone for stable CAD patients, challenging the clinical usefulness of such testing.
Ischaemic and viability testing for guiding PCI are overrated: pros and cons
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ORIGINAL RESEARCH

Mar 18
Bailout MANTA for transfemoral TAVI
This study evaluated the efficacy and safety of using the MANTA plug-based vascular closure device in 66 patients experiencing failed suture-based closure during transfemoral TAVI, finding it achieved haemostasis in 75.8% without complications in 86.4%.
Bailout MANTA for transfemoral TAVI
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Comparative preclinical assessment of DCBs

EDITORIAL

Mar 18
Comparative preclinical assessment of DCBs
Michael Joner; Léa Wild
A study compared three drug-coated balloon formulations in a porcine model, assessing drug transfer and tissue distribution as surrogates for clinical efficacy. Both paclitaxel formulations showed greater smooth muscle cell loss than the sirolimus formulation, but limitations were present.
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Mar 25
#EIJonAir - CMD in aortic stenosis

Join our upcoming live Twitter video chat on on Characterisation of coronary microvascular dysfunction in patients with severe aortic stenosis undergoing TAVI with Salvatore Brugaletta and Roberto Scarsini.


Join our upcoming live Twitter video chat on March 28th at 6:00 PM (CET - Paris time)

#EIJonAir - CMD in aortic stenosis

ORIGINAL RESEARCH

Mar 4
SAPT following Amplatzer LAAO
Anders Kramer, Jens Erik Nielsen-Kudsk et al.
This study evaluated the safety and efficacy of single antiplatelet therapy as the sole post-procedural antithrombotic regimen following left atrial appendage occlusion in 431 high bleeding risk patients, finding low rates of adverse events comparable to more intensive regimens.
SAPT following Amplatzer LAAO

EDITORIAL

Mar 18
Plug-based bailout after failed suture-based large-bore vascular access closure: one more arrow in the quiver for experienced hands?
Tobias Rheude; Erion Xhepa
The ACCESS-TAVI trial randomly assigned 526 patients undergoing transfemoral TAVI to either closure of the femoral artery access site with a vascular closure device or manual compression. No significant differences were found between groups for major or minor vascular complications within 30 days.
Plug-based bailout after failed suture-based large-bore vascular access closure: one more arrow in the quiver for experienced hands?
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ORIGINAL ARTICLE

Mar 7
μQFR for functional assessment of ICAS
Kangmo Huang, Xinfeng Liu et al.
This study evaluated haemodynamic significance of intracranial atherosclerotic stenosis using quantitative flow ratio analysis in 412 patients, finding it outperformed stenosis severity in identifying culprit lesions and a nomogram integrating it and risk factors effectively stratified stroke risk.
μQFR for functional assessment of ICAS

DEBATE

Mar 4
Prophylactic stenting of vulnerable plaques: pros and cons
Duk-Woo Park, David L. Brown et al.
This study discusses preventive stenting of vulnerable plaques to reduce acute coronary syndromes risk but current imaging has limitations and stenting risks harm, requiring larger trials to prove risks and benefits.
Prophylactic stenting of vulnerable plaques: pros and cons
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EXPERT REVIEW

Feb 19
Evolving indications for edge-to-edge repair
Mony Shuvy, Francesco Maisano

This expert review examines the use of transcatheter mitral edge-to-edge repair (TEER) in patient populations beyond current indications, discussing the outcomes and limitations seen in these diverse patient groups.

Evolving indications for edge-to-edge repair
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Preclinical evaluation of the degradation kinetics of third-generation resorbable magnesium scaffolds
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Eltchaninoff H et al
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The Official Journal of EuroPCR and the European Association of Percutaneous Cardiovascular Interventions (EAPCI)

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2022 Journal Citation Reports®
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Online ISSN 1969-6213 - Print ISSN 1774-024X
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