Residents’ Papers GynecologyUrinary incontinence and pelvic organ prolapse in women with Marfan or Ehlers-Danlos syndrome☆
Section snippets
Material and methods
A medical records search of all women 18 years of age or greater with an International Classification of Diseases, Ninth Revision diagnosis code of either Marfan syndrome or Ehlers-Danlos syndrome was performed at an urban university-associated medical center and at an urban community-based teaching hospital. Through telephone interview each patient answered a series of items that included demographic information and gynecologic, urologic, obstetric, medical, surgical, and social histories.
Results
The medical records search by International Classification of Diseases, Ninth Revision diagnosis codes identified 19 women with Marfan syndrome and 10 women with Ehlers-Danlos syndrome. Among those with Marfan syndrome, 5 were dead and 2 were not available for interview. Two of the 10 women with Ehlers-Danlos syndrome were not available for interview. The remaining 12 patients with Marfan syndrome and 8 patients with Ehlers-Danlos syndrome were used for statistical analysis.
Demographic and
Comment
Although several case reports and small series have described potential obstetric risks among patients with Marfan syndrome and Ehlers-Danlos syndrome, little information regarding gynecologic and urologic complications exists. In this series we found high rates of both urinary incontinence and pelvic organ prolapse among women with either Marfan syndrome or Ehlers-Danlos syndrome. These findings are notable in light of the young mean age and relatively low median parity of both groups. It is
References (10)
- et al.
Obstetric history in women with surgically corrected adult urinary incontinence or pelvic organ prolapse
J Am Assoc Gynecol Laparosc
(1999) - et al.
Connective tissues disorders in obstetrics and gynecology
Am J Obstet Gynecol
(1968) - et al.
Elucidation of the gene defect in Marfan syndrome
FEBS Lett
(1992) - et al.
Prevalence, incidence and correlates of urinary incontinence in healthy, middle-aged women
J Urol
(1991) - et al.
The prevalence of urinary incontinence or prolapse among white and Hispanic women
Am J Obstet Gynecol
(1996)
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Reprint requests: Michael E. Carley, MD, Department of Obstetrics and Gynecology, Division of Gynecologic Surgery, Mayo Graduate School of Medicine, 200 First St SW, Rochester, MN 55905.