Elsevier

Value in Health

Volume 15, Issue 6, September–October 2012, Pages 796-803
Value in Health

ISPOR Task Force report
Modeling Good Research Practices—Overview: A Report of the ISPOR-SMDM Modeling Good Research Practices Task Force-1

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Abstract

Models—mathematical frameworks that facilitate estimation of the consequences of health care decisions—have become essential tools for health technology assessment. Evolution of the methods since the first ISPOR Modeling Task Force reported in 2003 has led to a new Task Force, jointly convened with the Society for Medical Decision Making, and this series of seven articles presents the updated recommendations for best practices in conceptualizing models; implementing state-transition approaches, discrete event simulations, or dynamic transmission models; and dealing with uncertainty and validating and reporting models transparently. This overview article introduces the work of the Task Force, provides all the recommendations, and discusses some quandaries that require further elucidation. The audience for these articles includes those who build models, stakeholders who utilize their results, and, indeed, anyone concerned with the use of models to support decision making.

Keywords

best practices
guidelines
methods
modeling

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Conflict of Interest Statement: All members of the Task Force include modeling activities among their professional practices and in many cases these are funded by organizations with interest in the results. Some members of the Task Force own intellectual property relating to models. Many of the points made in these articles are supported by citations to articles authored by Task Force members. The Task Force took pains to avoid commercial considerations influencing the deliberations or the content of these articles.