Clinical ResearchBiomarkersUse of Amino-Terminal Pro–B-Type Natriuretic Peptide to Guide Outpatient Therapy of Patients With Chronic Left Ventricular Systolic Dysfunction
Biomarkers
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Key Words
heart failure
natriuretic peptides
outcomes
Abbreviations and Acronyms
GEE
generalized estimating equations
HF
heart failure
HFpEF
heart failure with preserved ejection fraction
LV
left ventricular
LVSD
left ventricular systolic dysfunction
NT-proBNP
amino-terminal pro–B-type natriuretic peptide
QOL
quality of life
SOC
standard of care
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This study was supported in part by Roche Diagnostics, Inc. Dr. Januzzi is supported in part by the Balson Cardiac Scholar Fund; has received research grants and consultancy fees from Roche Diagnostics, Inc., Siemens Diagnostics, and Critical Diagnostics; and has received speakers fees from Roche Diagnostics, Inc. and Siemens Diagnostics. Drs. Rehman, Mohammed, Bhardwaj, and Kim are supported by the Dennis and Marilyn Barry Cardiology Fellowship. Dr. Shin has served as a consultant to Acceleron Pharma. Dr. Wang has been a coinvestigator on studies that received assay support from Siemens Diagnostics. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.
Copyright © 2011 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.