Clinical ResearchHeart FailureReal-Time Dynamic Carbon Dioxide Administration: A Novel Treatment Strategy for Stabilization of Periodic Breathing With Potential Application to Central Sleep Apnea
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Supported by National Institute for Health Research Biomedical Research Centrefunding scheme. Dr. Giannoni was supported by a European Society of Cardiologyresearch grant. Dr. Baruah (PG/07/065) and Dr. Francis (FS/04/079) were supported by the British Heart Foundation. K. Willson and Dr. Mebrate received support from the Foundation for Circulatory Health(ICCH/05/5004). C. Manisty received support from the Wellcome Trust(077049/Z/05/Z). All other authors have reported that they have no relationships to disclose. Drs. Giannoni and Baruah contributed equally to this work; the studies of voluntary periodic breathing were predominantly conducted by Dr. Giannoni and the studies of the heart failure patients were predominantly conducted by Dr. Baruah.