Journal of the American Society of Echocardiography
Original articleEffect of Preload Augmentation on Pulsed Wave and Tissue Doppler Echocardiographic Indices of Diastolic Function After a Marathon
Section snippets
Participants
After approval from our ethics committee, 14 trained athletes (13 male; mean ± SD; age 34 ± 7 years, height 1.77 ± 0.07 m, body mass 78.0 ± 8.2 kg) competing in the 2005 London Marathon provided written informed consent to participate in the study. Exclusion criteria included any personal or early family history of cardiopulmonary diseases.
Design
Participants were assessed 24 hours before the marathon and within 30 minutes of race completion. Identical procedures were completed on both occasions. Body
Results
Marathon completion time was 216 ± 40 minutes and all participants returned for postrace assessment within 30 minutes of race completion. Body mass was significantly reduced (78 ± 8 vs 75 ± 8 kg, P < .05).
Discussion
The current data provide unique evidence of altered LV diastolic function after a marathon, which can be partially reversed by returning preload toward pre-exercise levels. This effect is, however, partly dependent on the specific diastolic functional variable assessed.
References (31)
- et al.
Preload dependence of Doppler-derived indexes of LV diastolic function in humans
J Am Coll Cardiol
(1987) - et al.
Which Doppler parameters are preload independent?A study in normal volunteers after blood donation
J Am Soc Echocardiogr
(2005) - et al.
Doppler tissue imaging and color M-mode flow propagation velocity: are they really preload independent?
J Am Soc Echocardiogr
(2005) - et al.
Left ventricular flow propagation velocity during early filling is related to wall relaxation: a color M-mode Doppler analysis
J Am Coll Cardiol
(1992) - et al.
A practical approach to echocardiographic evaluation of diastolic function
J Am Soc Echocardiogr
(2004) - et al.
Persistent and reversible cardiac dysfunction among amateur marathon runners
Eur Heart J
(2006) - et al.
Novel application of flow propagation velocity and ischemia modified albumin in analysis of post-exercise cardiac function
Exp Physiol
(2006) - et al.
Mitral annular myocardial velocity assessment of segmental left ventricular diastolic function after prolonged exercise in humans
J Physiol
(2005) - et al.
Impact of marathon running on cardiac structure and function in recreational runners
Clin Sci (Colch)
(2005) - et al.
Short-term effects of marathon running: no evidence of cardiac dysfunction
Med Sci Sports Exerc
(1999)