Original articleAdult cardiacTransfusion and Pulmonary Morbidity After Cardiac Surgery
Section snippets
Patients
Between September 1998 and February 2006, 16,847 patients underwent coronary artery bypass grafting (CABG), a valve procedure, or combination of CABG and valve surgery at Cleveland Clinic. Baseline demographics and perioperative variables were obtained from the Department of Cardiothoracic Anesthesia Registry. Registry information was prospectively collected concurrent with patient care by trained database personnel. The Cardiovascular Information Registry, a similar prospective registry, was
Pulmonary Morbidity and Transfusion
A total of 79,530 red blood cell and component blood product units were transfused. Among propensity-matched patients, those who received RBC transfusion had more pulmonary morbidity postoperatively (Table 1). They had longer intubation time, higher prevalence of respiratory distress and failure, and more frequently required reintubation for pulmonary-related reasons. Prevalence of ARDS was higher. They also had more readmissions to the ICU, and longer overall ICU length of stay.
Among matched
Comment
We report that transfusion was associated with a higher risk-adjusted prevalence of respiratory distress and failure, ARDS, reintubation for pulmonary-related reasons, longer total intubation time, more readmissions to the ICU for pulmonary-related reasons, and longer ICU length of stay. Similarly, FFP transfusion was associated with significantly more pulmonary complications in the postoperative period. Surprisingly, a substantial proportion of patients manifested (Pao2/Fio2 < 300) for both
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2022, Journal of Thoracic and Cardiovascular SurgeryCitation Excerpt :In contrast, late CPB was associated with longer bypass times in the low anatomic risk cohort, a finding that might be explained by factors related to operating surgeon and case mix. Several studies have linked perioperative red blood cell transfusion with worse outcomes in cardiac surgical patients.18,19 Although a higher percentage of patients received intraoperative blood transfusions in the early CPB group, more units of platelets and cryoprecipitate were transfused in the late CPB group in the high-risk cohort.